C₃₃H₅₀N₁₀O₇Si₂

Base Information

• Chemical Name: C₃₃H₅₀N₁₀O₇Si₂
• CAS No.: 1355611-01-6
• Molecular Formula: C₃₃H₅₀N₁₀O₇Si₂
• Molecular Weight: 754.994
• Mol file: 1355611-01-6.mol

Synonyms:C₃₃H₅₀N₁₀O₇Si₂

Chemical Property of C₃₃H₅₀N₁₀O₇Si₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₃H₅₀N₁₀O₇Si₂

There total 6 articles about C₃₃H₅₀N₁₀O₇Si₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

C34H50F3N7O10SSi2 (1355611-00-5) → C33H50N10O7Si2 (1355611-01-6)

Guidance literature:

With lithium azide; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

DOI:10.1021/cb200510k

Reference yield:

3',5'-O-1,1,3,3-tetraisopropyldisiloxan-1,3-diyl-guanosine (69304-44-5) → C33H50N10O7Si2 (1355611-01-6)

Guidance literature:

Multi-step reaction with 6 steps

1: N,N-dimethyl-formamide / 6 h / 20 °C

2: di-isopropyl azodicarboxylate; triphenylphosphine / 1,4-dioxane / 16 h / 20 °C

3: dmap / dichloromethane / 0.5 h / 0 °C

4: 18-crown-6 ether; potassium trifluoroacetate; N-ethyl-N,N-diisopropylamine / toluene / 16 h / 80 °C

5: dmap; triethylamine / dichloromethane / 0.25 h / 0 °C

6: lithium azide / N,N-dimethyl-formamide / 16 h / 20 °C

With dmap; lithium azide; 18-crown-6 ether; di-isopropyl azodicarboxylate; potassium trifluoroacetate; triethylamine; N-ethyl-N,N-diisopropylamine; triphenylphosphine; In 1,4-dioxane; dichloromethane; N,N-dimethyl-formamide; toluene;

DOI:10.1021/cb200510k

Reference yield:

C34H50F3N7O10SSi2 (1355610-98-8) → C33H50N10O7Si2 (1355611-01-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 18-crown-6 ether; potassium trifluoroacetate; N-ethyl-N,N-diisopropylamine / toluene / 16 h / 80 °C

2: dmap; triethylamine / dichloromethane / 0.25 h / 0 °C

3: lithium azide / N,N-dimethyl-formamide / 16 h / 20 °C

With dmap; lithium azide; 18-crown-6 ether; potassium trifluoroacetate; triethylamine; N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide; toluene;

DOI:10.1021/cb200510k

upstream raw materials:

3',5'-O-1,1,3,3-tetraisopropyldisiloxan-1,3-diyl-guanosine

C₃₃H₅₁N₇O₈Si₂

C₃₄H₅₀F₃N₇O₁₀SSi₂

C₃₃H₅₁N₇O₈Si₂

Downstream raw materials:

C₂₁H₂₄N₁₀O₆

C₄₂H₄₂N₁₀O₈

C₆H₁₅N*C₄₈H₄₆ClN₁₀O₁₁P