(+/-)-anisomycin

Base Information

Chemical Name:(+/-)-anisomycin
CAS No.:21497-40-5
Molecular Formula:C₁₄H₁₉NO₄
Molecular Weight:265.309
Hs Code.:

Synonyms:(+/-)-anisomycin

Suppliers and Price of (+/-)-anisomycin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of (+/-)-anisomycin

Chemical Property:

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+/-)-anisomycin

There total 11 articles about (+/-)-anisomycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1963-42-4
2-(p-methoxybenzyl)pyrrole

: 21497-40-5
(+/-)-anisomycin

Guidance literature:: Multi-step reaction with 9 steps

1: 67 percent / zinc dust, aq. HCl / ethanol / 1.) 1.5 h, 2.) reflux, 1.5 h

2: 94 percent / aq. NaOH / toluene / 1 h / 3 - 5 °C

3: 82 percent / N-iodosuccinimide, aq. perchloric acid / tetrahydrofuran / 1.) 3-5 deg C, 1 h, 2.) 3-5 deg C -> room temperature, 1 h

4: 92 percent / 5percent KOH, EtOH / 0.5 h

5: 100 percent / hydrogen / 10percent Pd/C / methanol / 2 h

6: trifluoroacetic acid, sodium trifluoroacetate / 16 h / Heating

7: aq. Na₂CO₃ / tetrahydrofuran / 1 h / 3 - 5 °C / pH 9

8: 1.) pyridine, 2.) pyridine / 1.) CH₂Cl₂, 3-5 deg C, 30 min, 2.) 18 h

9: 1.) zinc powder, acetic acid, 2.) hydrogen / 2.) 10percent Pd/C / 1.) THF, 1 h, 2.) MeOH, 2 h

With pyridine; hydrogenchloride; potassium hydroxide; sodium hydroxide; N-iodo-succinimide; perchloric acid; ethanol; hydrogen; sodium 2,2,2-trifluoroacetate; sodium carbonate; acetic acid; trifluoroacetic acid; zinc; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol; toluene;
DOI:10.1021/ja00386a039

Reference yield:

: 22862-67-5
2-[(4-methoxyphenyl)methyl]-2,5-dihydro-(1H)-pyrrole

: 21497-40-5
(+/-)-anisomycin

Guidance literature:: Multi-step reaction with 8 steps

1: 94 percent / aq. NaOH / toluene / 1 h / 3 - 5 °C

2: 82 percent / N-iodosuccinimide, aq. perchloric acid / tetrahydrofuran / 1.) 3-5 deg C, 1 h, 2.) 3-5 deg C -> room temperature, 1 h

3: 92 percent / 5percent KOH, EtOH / 0.5 h

4: 100 percent / hydrogen / 10percent Pd/C / methanol / 2 h

5: trifluoroacetic acid, sodium trifluoroacetate / 16 h / Heating

6: aq. Na₂CO₃ / tetrahydrofuran / 1 h / 3 - 5 °C / pH 9

7: 1.) pyridine, 2.) pyridine / 1.) CH₂Cl₂, 3-5 deg C, 30 min, 2.) 18 h

8: 1.) zinc powder, acetic acid, 2.) hydrogen / 2.) 10percent Pd/C / 1.) THF, 1 h, 2.) MeOH, 2 h

With pyridine; potassium hydroxide; sodium hydroxide; N-iodo-succinimide; perchloric acid; ethanol; hydrogen; sodium 2,2,2-trifluoroacetate; sodium carbonate; acetic acid; trifluoroacetic acid; zinc; palladium on activated charcoal; In tetrahydrofuran; methanol; toluene;
DOI:10.1021/ja00386a039

Reference yield:

: 24064-16-2
benzyl 2-[(4-methoxyphenyl)methyl]-2,5-dihydropyrrole-1-carboxylate

: 21497-40-5
(+/-)-anisomycin

Guidance literature:: Multi-step reaction with 7 steps

1: 82 percent / N-iodosuccinimide, aq. perchloric acid / tetrahydrofuran / 1.) 3-5 deg C, 1 h, 2.) 3-5 deg C -> room temperature, 1 h

2: 92 percent / 5percent KOH, EtOH / 0.5 h

3: 100 percent / hydrogen / 10percent Pd/C / methanol / 2 h

4: trifluoroacetic acid, sodium trifluoroacetate / 16 h / Heating

5: aq. Na₂CO₃ / tetrahydrofuran / 1 h / 3 - 5 °C / pH 9

6: 1.) pyridine, 2.) pyridine / 1.) CH₂Cl₂, 3-5 deg C, 30 min, 2.) 18 h

7: 1.) zinc powder, acetic acid, 2.) hydrogen / 2.) 10percent Pd/C / 1.) THF, 1 h, 2.) MeOH, 2 h

With pyridine; potassium hydroxide; N-iodo-succinimide; perchloric acid; ethanol; hydrogen; sodium 2,2,2-trifluoroacetate; sodium carbonate; acetic acid; trifluoroacetic acid; zinc; palladium on activated charcoal; In tetrahydrofuran; methanol;
DOI:10.1021/ja00386a039