dimethyl(phenyl)silanecarboxylic acid

Base Information

• Chemical Name: dimethyl(phenyl)silanecarboxylic acid
• CAS No.: 17878-13-6
• Molecular Formula: C₉H₁₂O₂Si
• Molecular Weight: 180.279
• Mol file: 17878-13-6.mol

Synonyms:dimethyl(phenyl)silanecarboxylic acid

Chemical Property of dimethyl(phenyl)silanecarboxylic acid

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of dimethyl(phenyl)silanecarboxylic acid

There total 2 articles about dimethyl(phenyl)silanecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

carbon dioxide (124-38-9,18923-20-1) + phenyldimethylsilyl chloride (768-33-2) → dimethyl(phenyl)silanecarboxylic acid (17878-13-6)

Guidance literature:

phenyldimethylsilyl chloride; With lithium; In tetrahydrofuran; at 20 ℃; for 5h; Inert atmosphere;

carbon dioxide; In tetrahydrofuran; at -78 ℃; for 0.333333h; Inert atmosphere;

DOI:10.1021/ja208652n

Reference yield:

→ dimethyl(phenyl)silanecarboxylic acid (17878-13-6)

Guidance literature:

Dimethyl-phenyl-silyllithium, THF, Eingiessen in Gemisch von Ae. u. festem CO2;

DOI:10.1021/jo01082a029

Reference yield: 93.0%

p-methoxycarbonyl-1,1-diphenylethylene (29265-82-5) + dimethyl(phenyl)silanecarboxylic acid (17878-13-6) → C24H26O2Si

Guidance literature:

With (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; In acetonitrile; at 20 ℃; for 12h; chemoselective reaction; Inert atmosphere; Sealed tube; Irradiation;

DOI:10.1002/anie.202003070

upstream raw materials:

carbon dioxide

phenyldimethylsilyl chloride

Downstream raw materials:

tetrakis(μ-phenyldimethylsilanecarboxylato)bis[aquocopper(II)]

PhMe₂Si-O₂C-SiMe₂Ph

dimethylphenylsilanol

benzyl 3-(dimethyl(phenyl)silyl)propanoate

Refernces

• 1、 Liang, Jin-Yan,Shen, Shou-Jie,Xu, Xiao-Hu,Fu, Yun-Long. "Synthesis of Aryl Silacarboxylates via Palladium-Catalyzed C-O Bond Formation of Silacarboxylic Acids and Aryl Iodides". supporting information. p. 6627 - 6631. Retrieved 2018/10/31.