29265-82-5

Upstream product

• 98-81-7 1-bromovinylbenzene 
• 99768-12-4 4-methoxycarbonylphenylboronic acid 
• 98-86-2 acetophenone 
• 171364-80-0 methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 
• 586-76-5 4-Bromobenzoic acid 
• 4545-21-5 acetophenone p-toluenesulfonylhydrazone 
• 6158-54-9 methyl 4-Benzoylbenzoate 
• 1779-49-3 Methyltriphenylphosphonium bromide 
• 4333-76-0 1-(4-bromophenyl)-1-phenylethene 
• 81329-28-4 1-(4-cyanophenyl)-1-phenylethylene 
• 77-78-1 dimethyl sulfate 
• 611-95-0 4-carboxybenzophenone 

Downstream Products

• 1420475-71-3 C₁₇H₁₈O₃ 

Relevant academic research and scientific papers

The Concept of Photozymes: Short Peptides with Photoredox Catalytic Activity for Nucleophilic Additions to α-Phenyl Styrenes

Conventional photoredox catalytic additions of alcohols to olefins require additives, like thiophenol, to promote back electron transfer. The concept of “photozymes” assumes that forward and backward electron transfer steps in a photoredox catalytic cycle

PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS

This disclosure provides pharmaceutical compounds to treat medical disorders, such as complement-mediated disorders, including complement Cl -mediated disorders.

Catalyst-Free Enantiospecific Olefination with In Situ Generated Organocerium Species

Described is the in situ formation of triorganocerium reagents and their application in catalyst-free Zweifel olefinations. These unique cerium species were generated through novel exchange reactions of organohalides with n-Bu3Ce reagents. The adequate electronegativity of cerium allowed for compensating the disadvantages of both usually functional-group-sensitive organolithium species and less reactive organomagnesium reagents. Exchange reactions were performed on aryl and alkenyl bromides, enabling enantiospecific transformations of chiral boron pinacol esters. Finally, these new organocerium species were engaged in selective 1,2-additions onto enolisable and sterically hindered ketones.

Nickel-Catalyzed Direct Synthesis of Aryl Olefins from Ketones and Organoboron Reagents under Neutral Conditions

Nickel-catalyzed addition of arylboron reagents to ketones results in aryl olefins directly. The neutral condition allows acidic protons of alcohols, phenols, and malonates to be present, and fragile structures are also tolerated.

Mn(OAc)3-Mediated Synthesis of 3-Phosphonyldihydrofurans from β-Ketophosphonates and Alkenes

A new, general method for the synthesis of 3-phosphonyldihydrofuran derivatives has been achieved through Mn(OAc)3-mediated radical cyclization between β-ketophosphonates and alkenes. This transformation allows the direct formation of C-C/C-O bonds and the construction of a dihydrofuran ring in one reaction with operational simplicity and excellent functional-group compatibility.