(2S,4R)-1-(tert-butoxycarbonyl)-4-(4-fluoro-2-methylbenzyl)pyrrolidine-2-carboxylic acid

Base Information

Chemical Name:(2S,4R)-1-(tert-butoxycarbonyl)-4-(4-fluoro-2-methylbenzyl)pyrrolidine-2-carboxylic acid
CAS No.:1222196-24-8
Molecular Formula:C₁₈H₂₄FNO₄
Molecular Weight:337.391
Hs Code.:

Synonyms:(2S,4R)-1-(tert-butoxycarbonyl)-4-(4-fluoro-2-methylbenzyl)pyrrolidine-2-carboxylic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2S,4R)-1-(tert-butoxycarbonyl)-4-(4-fluoro-2-methylbenzyl)pyrrolidine-2-carboxylic acid

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Technology Process of (2S,4R)-1-(tert-butoxycarbonyl)-4-(4-fluoro-2-methylbenzyl)pyrrolidine-2-carboxylic acid

There total 1 articles about (2S,4R)-1-(tert-butoxycarbonyl)-4-(4-fluoro-2-methylbenzyl)pyrrolidine-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.8%

: 24424-99-5
di-tert-butyl dicarbonate

: 1222196-27-1
(2S,4R)-4-(4-fluoro-2-methylbenzyl)pyrrolidine-2-carboxylic acid trifluoroacetate

: 1222196-24-8
(2S,4R)-1-(tert-butoxycarbonyl)-4-(4-fluoro-2-methylbenzyl)pyrrolidine-2-carboxylic acid

Guidance literature:: di-tert-butyl dicarbonate; (2S,4R)-4-(4-fluoro-2-methylbenzyl)pyrrolidine-2-carboxylic acid trifluoroacetate; With N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; acetonitrile; at 20 ℃; for 24h;

With sodium hydrogencarbonate; In water;

With 1-hydroxy-1,1,2-ethanetricarboxylic acid; In water; pH=4;