3-(3-(4-chlorophenyl)-1-(4-methoxyphenyl)prop-2-yn-1-yl)-1-methyl-1H-indole

Base Information

Chemical Name:3-(3-(4-chlorophenyl)-1-(4-methoxyphenyl)prop-2-yn-1-yl)-1-methyl-1H-indole
CAS No.:1403848-69-0
Molecular Formula:C₂₅H₂₀ClNO
Molecular Weight:385.893
Hs Code.:

Synonyms:3-(3-(4-chlorophenyl)-1-(4-methoxyphenyl)prop-2-yn-1-yl)-1-methyl-1H-indole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(3-(4-chlorophenyl)-1-(4-methoxyphenyl)prop-2-yn-1-yl)-1-methyl-1H-indole

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Technology Process of 3-(3-(4-chlorophenyl)-1-(4-methoxyphenyl)prop-2-yn-1-yl)-1-methyl-1H-indole

There total 1 articles about 3-(3-(4-chlorophenyl)-1-(4-methoxyphenyl)prop-2-yn-1-yl)-1-methyl-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 603-76-9
1-methylindole

: 89891-82-7
(4-chlorophenyl)ethynyl iodide

: 123-11-5
4-methoxy-benzaldehyde

: 1403848-69-0
3-(3-(4-chlorophenyl)-1-(4-methoxyphenyl)prop-2-yn-1-yl)-1-methyl-1H-indole

Guidance literature:: 1-methylindole; (4-chlorophenyl)ethynyl iodide; 4-methoxy-benzaldehyde; With bis(cyclopentadienyl)titanium dichloride; tri-tert-butyl phosphine; zinc; In 1,2-dichloro-ethane; at 20 ℃; for 1h; Inert atmosphere;

With acetic anhydride; caesium carbonate; In 1,2-dichloro-ethane; at 20 ℃; for 11h; Inert atmosphere;
DOI:10.1021/ja308891e DOI:10.1021/ja308891e