N'-(1-(benzo[d][1,3]dioxol-5-yl)butylidene)-4-methylbenzenesulfonohydrazide

Base Information

• Chemical Name: N'-(1-(benzo[d][1,3]dioxol-5-yl)butylidene)-4-methylbenzenesulfonohydrazide
• CAS No.: 1220985-67-0
• Molecular Formula: C₁₈H₂₀N₂O₄S
• Molecular Weight: 360.434
• Mol file: 1220985-67-0.mol

Synonyms:N'-(1-(benzo[d][1,3]dioxol-5-yl)butylidene)-4-methylbenzenesulfonohydrazide

Chemical Property of N'-(1-(benzo[d][1,3]dioxol-5-yl)butylidene)-4-methylbenzenesulfonohydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N'-(1-(benzo[d][1,3]dioxol-5-yl)butylidene)-4-methylbenzenesulfonohydrazide

There total 1 articles about N'-(1-(benzo[d][1,3]dioxol-5-yl)butylidene)-4-methylbenzenesulfonohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

1-(2H-benzo[3,4-d]1,3-dioxolen-5-yl)butan-1-one (63740-97-6) + toluene-4-sulfonic acid hydrazide (1576-35-8) → N'-(1-(benzo[d][1,3]dioxol-5-yl)butylidene)-4-methylbenzenesulfonohydrazide (1220985-67-0)

Guidance literature:

In methanol; Reflux;

DOI:10.1039/b925590g

Reference yield: 84.0%

N'-(1-(benzo[d][1,3]dioxol-5-yl)butylidene)-4-methylbenzenesulfonohydrazide (1220985-67-0) + 4-methoxyphenylboronic acid (5720-07-0) → 5-(1-(4-methoxyphenyl)but-1-enyl)benzo[d][1,3]dioxole

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; oxygen; copper(l) chloride; lithium tert-butoxide; In 1,4-dioxane; at 70 ℃;

DOI:10.1039/b925590g

Reference yield: 81.0%

N'-(1-(benzo[d][1,3]dioxol-5-yl)butylidene)-4-methylbenzenesulfonohydrazide (1220985-67-0) + 4-n-methylphenylacetylene (766-97-2) → 5-(1-p-tolylhex-3-en-1-yn-3-yl)benzo[d][1,3]dioxole (1301163-47-2)

Guidance literature:

With trifuran-2-yl-phosphane; palladium diacetate; p-benzoquinone; lithium tert-butoxide; In 1,4-dioxane; at 90 ℃; for 4h; stereoselective reaction; Inert atmosphere;

DOI:10.1002/anie.201007224

upstream raw materials:

1-(2H-benzo[3,4-d]1,3-dioxolen-5-yl)butan-1-one

toluene-4-sulfonic acid hydrazide

Downstream raw materials:

(Z)-5-(8-phenyloct-3-en-5-yn-4-yl)benzo[d][1,3]dioxole

(Z)-5-(1-(4-(trifluorometyl)phenyl)hex-3-en-1-yn-3-yl)benzo[d][1,3]dioxole

(Z)-5-(1-phenylhex-3-en-1-yn-3-yl)benzo[d][1,3]dioxole

5-(1-p-tolylhex-3-en-1-yn-3-yl)benzo[d][1,3]dioxole