ERYTHRO-4-(1-HYDROXY-2-HEXA-DECENYL)-2-PHENYL-2-OXAZOLINE

Base Information

Chemical Name:ERYTHRO-4-(1-HYDROXY-2-HEXA-DECENYL)-2-PHENYL-2-OXAZOLINE
CAS No.:161968-12-3
Molecular Formula:C₂₅H₃₉NO₂
Molecular Weight:385.59
Hs Code.:
Mol file:161968-12-3.mol

Synonyms:4-Oxazolemethanol,4,5-dihydro-a-(1E)-1-pentadecenyl-2-phenyl-,(aR,4S)-rel- (9CI);4-Oxazolemethanol, 4,5-dihydro-a-1-pentadecenyl-2-phenyl-, [R*,S*-(E)]-

Suppliers and Price of ERYTHRO-4-(1-HYDROXY-2-HEXA-DECENYL)-2-PHENYL-2-OXAZOLINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
erythro-4-(1-Hydroxy-2-hexadecenyl)-2-phenyl-2-oxazoline
5mg
$ 458.00

Total 2 raw suppliers

Chemical Property of ERYTHRO-4-(1-HYDROXY-2-HEXA-DECENYL)-2-PHENYL-2-OXAZOLINE

Chemical Property:

Boiling Point:515.1±23.0 °C(Predicted)
PKA:13.48±0.20(Predicted)
PSA：41.82000
Density:1.00±0.1 g/cm3(Predicted)
LogP:5.88580
Storage Temp.:−20°C

Purity/Quality:

97% ^*data from raw suppliers

erythro-4-(1-Hydroxy-2-hexadecenyl)-2-phenyl-2-oxazoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of ERYTHRO-4-(1-HYDROXY-2-HEXA-DECENYL)-2-PHENYL-2-OXAZOLINE

There total 17 articles about ERYTHRO-4-(1-HYDROXY-2-HEXA-DECENYL)-2-PHENYL-2-OXAZOLINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.5%

: 15890-72-9
laurylmagnesium bromide

: 173531-24-3
(4S,1'S,2'R)-4-(1',2'-Epoxybut-3'-enyl)-2-phenyl-4,5-dihydrooxazole

: 78715-85-2,161968-12-3
erythro-4-(1-hydroxy-2-hexadecenyl)-2-phenyl-Δ²-oxazoline

Guidance literature:: With CuCN; In tetrahydrofuran; diethyl ether; at -70 - -50 ℃; for 0.5h;
DOI:10.1039/p19960000823

Reference yield: 90.0%

: 2-phenyl-4-(S)-[(4S,5S)-4-(tetradecyl)-1,3,2-dioxathiolane-2,2-dioxide-5-yl]-1,3-oxazoline

: 78739-31-8,161968-12-3
threo-4-(1-hydroxy-2-hexadecenyl)-2-phenyl-Δ²-oxazoline

Guidance literature:: 2-phenyl-4-(S)-[(4S,5S)-4-(tetradecyl)-1,3,2-dioxathiolane-2,2-dioxide-5-yl]-1,3-oxazoline; With tetra-(n-butyl)ammonium iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene; In toluene; at 70 ℃; for 5h; Reflux;

With sulfuric acid; water; In tetrahydrofuran; methanol; at 22 ℃; for 3h;
DOI:10.1002/ejoc.201100911

Reference yield:

: 78715-83-0
methyl (S)-2-phenyl-4,5-dihydrooxazole-4-carboxylate

: 78715-85-2,161968-12-3
erythro-4-(1-hydroxy-2-hexadecenyl)-2-phenyl-Δ²-oxazoline

Guidance literature:: Multi-step reaction with 2 steps

1: DIBAL-H / hexane; toluene / 3 h / -70 °C

2: 1.) DIBAL-H / 2.) ether, toluene, warming from 5 to 23 deg C, 1 h

With diisobutylaluminium hydride; In hexane; toluene;
DOI:10.1021/jo00335a015