2-(1-(2-methoxyethyl)-2-oxo-3-phenylpyrrolidin-3-ylamino)-2-oxoethyl 2-chloroacetate

Base Information

Chemical Name:2-(1-(2-methoxyethyl)-2-oxo-3-phenylpyrrolidin-3-ylamino)-2-oxoethyl 2-chloroacetate
CAS No.:1646848-61-4
Molecular Formula:C₁₇H₂₁ClN₂O₅
Molecular Weight:368.817
Hs Code.:

Synonyms:2-(1-(2-methoxyethyl)-2-oxo-3-phenylpyrrolidin-3-ylamino)-2-oxoethyl 2-chloroacetate

Suppliers and Price of 2-(1-(2-methoxyethyl)-2-oxo-3-phenylpyrrolidin-3-ylamino)-2-oxoethyl 2-chloroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(1-(2-methoxyethyl)-2-oxo-3-phenylpyrrolidin-3-ylamino)-2-oxoethyl 2-chloroacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(1-(2-methoxyethyl)-2-oxo-3-phenylpyrrolidin-3-ylamino)-2-oxoethyl 2-chloroacetate

There total 3 articles about 2-(1-(2-methoxyethyl)-2-oxo-3-phenylpyrrolidin-3-ylamino)-2-oxoethyl 2-chloroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 1646848-52-3
3-isocyano-1-(2-methoxyethyl)-3-phenylpyrrolidin-2-one

: 79-11-8
chloroacetic acid

: 1646848-61-4
2-(1-(2-methoxyethyl)-2-oxo-3-phenylpyrrolidin-3-ylamino)-2-oxoethyl 2-chloroacetate

Guidance literature:: In dichloromethane; at 20 ℃; for 18h; Inert atmosphere;
DOI:10.1002/ejoc.201402572

Reference yield:

: 39533-32-9
methyl 2-isocyano-2-phenylacetate

: 1646848-61-4
2-(1-(2-methoxyethyl)-2-oxo-3-phenylpyrrolidin-3-ylamino)-2-oxoethyl 2-chloroacetate

Guidance literature:: Multi-step reaction with 3 steps

1: caesium carbonate / acetonitrile / 4 h / Inert atmosphere; Reflux

2: dimethyl sulfoxide / 7 h / 80 °C / Inert atmosphere

3: dichloromethane / 18 h / 20 °C / Inert atmosphere

With caesium carbonate; In dichloromethane; dimethyl sulfoxide; acetonitrile;
DOI:10.1002/ejoc.201402572

Reference yield:

: 1646848-49-8
methyl 4-bromo-2-isocyano-2-phenylbutanoate

: 1646848-61-4
2-(1-(2-methoxyethyl)-2-oxo-3-phenylpyrrolidin-3-ylamino)-2-oxoethyl 2-chloroacetate

Guidance literature:: Multi-step reaction with 2 steps

1: dimethyl sulfoxide / 7 h / 80 °C / Inert atmosphere

2: dichloromethane / 18 h / 20 °C / Inert atmosphere

In dichloromethane; dimethyl sulfoxide;
DOI:10.1002/ejoc.201402572