39533-32-9Relevant articles and documents
Novel multicomponent reaction for the combinatorial synthesis of 2-imidazolines
Bon, Robin S.,Hong, Chongen,Bouma, Marinus J.,Schmitz, Rob F.,De Kanter, Frans J. J.,Lutz, Martin,Spek, Anthony L.,Orru, Romano V. A.
, p. 3759 - 3762 (2003)
(Matrix presented) The three-component condensation between an amine, an aldehyde, and an α-acidic isocyanide efficiently provides substituted 2-imidazolines in a one-pot reaction under mild conditions.
Catalytic enantioselective Michael addition of α-aryl-α- isocyanoacetates to vinyl selenone: Synthesis of α,α-disubstituted α-amino acids and (+)- and (-)-trigonoliimine A
Buyck, Thomas,Wang, Qian,Zhu, Jieping
, p. 12714 - 12718 (2013/12/04)
Be like Mike: The title reaction in the presence of the catalyst 1 afforded Michael adducts in excellent yields and enantioselectivities. The adducts were readily converted into α,α′-disubstituted α-amino acids. The enantioselective total synthesis of bot
