1-(Diphenyl-phosphinoyl)-3-ethyl-1-(methyl-phenyl-amino)-pentan-2-ol

Base Information

• Chemical Name: 1-(Diphenyl-phosphinoyl)-3-ethyl-1-(methyl-phenyl-amino)-pentan-2-ol
• CAS No.: 76527-74-7
• Molecular Formula: C₂₆H₃₂NO₂P
• Molecular Weight: 421.519
• Mol file: 76527-74-7.mol

Synonyms:1-(Diphenyl-phosphinoyl)-3-ethyl-1-(methyl-phenyl-amino)-pentan-2-ol

Chemical Property of 1-(Diphenyl-phosphinoyl)-3-ethyl-1-(methyl-phenyl-amino)-pentan-2-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 1-(Diphenyl-phosphinoyl)-3-ethyl-1-(methyl-phenyl-amino)-pentan-2-ol

There total 1 articles about 1-(Diphenyl-phosphinoyl)-3-ethyl-1-(methyl-phenyl-amino)-pentan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Ethylbutyraldehyde (97-96-1) + <(methylphenylamino)methyl>diphenylphosphine oxide (76527-75-8) → 1-(Diphenyl-phosphinoyl)-3-ethyl-1-(methyl-phenyl-amino)-pentan-2-ol (76527-74-7)

Guidance literature:

DOI:10.1016/S0040-4039(01)90556-8

Reference yield: 82.0%

1-(Diphenyl-phosphinoyl)-3-ethyl-1-(methyl-phenyl-amino)-pentan-2-ol (76527-74-7) → 3-Ethyl-1-(methyl-phenyl-amino)-pentan-2-one (79409-03-3)

Guidance literature:

In ethylene glycol; at 140 - 150 ℃; for 3h;

DOI:10.1016/S0040-4039(01)90556-8

Reference yield:

1-(Diphenyl-phosphinoyl)-3-ethyl-1-(methyl-phenyl-amino)-pentan-2-ol (76527-74-7) → (Z)-3-ethyl-1-(N-methylanilino)-1-pentene (76527-80-5) + (E)-3-ethyl-1-(N-methylanilino)-1-pentene (76527-79-2)

Guidance literature:

With potassium tert-butylate; In tetrahydrofuran; Yield given. Yields of byproduct given. Title compound not separated from byproducts; 1.) -78 deg C, 2 h; 2.) RT, 4 h;

upstream raw materials:

2-Ethylbutyraldehyde

<(methylphenylamino)methyl>diphenylphosphine oxide

Downstream raw materials:

3-Ethyl-1-(methyl-phenyl-amino)-pentan-2-one

(Z)-3-ethyl-1-(N-methylanilino)-1-pentene

(E)-3-ethyl-1-(N-methylanilino)-1-pentene