2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine

Base Information

• Chemical Name: 2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine
• CAS No.: 1349171-28-3
• Molecular Formula: C₁₇H₂₀BNO₂
• Molecular Weight: 281.162
• Mol file: 1349171-28-3.mol

Synonyms:2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine

Chemical Property of 2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine

Chemical Property:

• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

2-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)pyridine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine

There total 5 articles about 2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-phenylpyridine (1008-89-5) + bis(pinacol)diborane (73183-34-3) → 2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine (1349171-28-3)

Guidance literature:

With [RhCl₂(p-cymene)]2; C₃₃H₁₈F₆IrN₃⁽³⁺⁾; sodium t-butanolate; In tetrahydrofuran; at 20 ℃; for 18h; Sealed tube; Inert atmosphere; Irradiation;

DOI:10.1021/jacs.1c05859

Reference yield: 98.0%

2-phenylpyridine (1008-89-5) + bis(pinacol)diborane (73183-34-3) → 2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine (1349171-28-3) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8)

Guidance literature:

With catalyst: [Rh(OH)((CHCHC₂H₄)2)]2/Silica-SMAP; In tetrahydrofuran; for 1 h at room temp.;

DOI:10.1021/ja208364a

Reference yield: 71.0%

2-phenylpyridine (1008-89-5) + 4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane (25015-63-8) → 2-[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]pyridine (1349171-28-3)

Guidance literature:

With [Rh(OH)(cod)]2; In tetrahydrofuran; at 60 ℃; for 12h; regioselective reaction; Inert atmosphere;

DOI:10.1021/ja208364a

upstream raw materials:

2-phenylpyridine

bis(pinacol)diborane

4,4,5,5-tetramethyl-[1,3,2]-dioxaboralane

2-(2-fluorophenyl)pyridine

Downstream raw materials:

2-(pyridine-2-yl)phenol