3-phenyl-5-[(phenylsulfanyl)methyl]-4,5-dihydro-1,2-oxazole

Base Information

• Chemical Name: 3-phenyl-5-[(phenylsulfanyl)methyl]-4,5-dihydro-1,2-oxazole
• CAS No.: 101024-70-8
• Molecular Formula: C₁₆H₁₅NOS
• Molecular Weight: 269.367
• Mol file: 101024-70-8.mol

Synonyms:3-phenyl-5-[(phenylsulfanyl)methyl]-4,5-dihydro-1,2-oxazole

Chemical Property of 3-phenyl-5-[(phenylsulfanyl)methyl]-4,5-dihydro-1,2-oxazole

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-phenyl-5-[(phenylsulfanyl)methyl]-4,5-dihydro-1,2-oxazole

There total 7 articles about 3-phenyl-5-[(phenylsulfanyl)methyl]-4,5-dihydro-1,2-oxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

sodium thiophenolate (930-69-8) + (3-phenyl-4,5-dihydro-1,2-oxazol-5-yl)methyl 4-methylbenzene-1-sulfonate → 3-phenyl-5-[(phenylsulfanyl)methyl]-4,5-dihydro-1,2-oxazole (101024-70-8)

Guidance literature:

In acetone; at 80 ℃; for 6h;

DOI:10.1039/c9ob02424g

Reference yield: 80.0%

N-(phenylthio)succinimide (14204-24-1) + (E)-1-phenylbut-3-en-1-one oxime (68843-67-4) → 3-phenyl-5-[(phenylsulfanyl)methyl]-4,5-dihydro-1,2-oxazole (101024-70-8)

Guidance literature:

With boron trifluoride diethyl etherate; In 1,2-dichloro-ethane; at 20 ℃; for 4h;

DOI:10.1039/d0ob01388a

Reference yield: 64.0%

1-phenyl-but-3-en-1-one oxime (68843-67-4) + diphenyldisulfane (882-33-7) → 3-phenyl-5-[(phenylsulfanyl)methyl]-4,5-dihydro-1,2-oxazole (101024-70-8)

Guidance literature:

With [bis(acetoxy)iodo]benzene; 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 20 ℃; for 6h; Inert atmosphere;

DOI:10.1039/c7ob02892j

upstream raw materials:

1-nitro-1-phenylmethane

allyl phenyl thioether

1-phenyl-but-3-en-1-one oxime

diphenyldisulfane

Downstream raw materials:

4-Amino-4-phenyl-1-phenylsulfanyl-butan-2-ol

N-(3-Hydroxy-1-phenyl-4-phenylsulfanyl-butyl)-benzamide