(+)-(1'S,2'S,2S,3R)-2-ethyl-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N-methyl-3-phenylpentanamide

Base Information

Chemical Name:(+)-(1'S,2'S,2S,3R)-2-ethyl-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N-methyl-3-phenylpentanamide
CAS No.:897920-47-7
Molecular Formula:C₂₃H₃₁NO₂
Molecular Weight:353.505
Hs Code.:

Synonyms:(+)-(1'S,2'S,2S,3R)-2-ethyl-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N-methyl-3-phenylpentanamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (+)-(1'S,2'S,2S,3R)-2-ethyl-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N-methyl-3-phenylpentanamide

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Technology Process of (+)-(1'S,2'S,2S,3R)-2-ethyl-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N-methyl-3-phenylpentanamide

There total 1 articles about (+)-(1'S,2'S,2S,3R)-2-ethyl-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N-methyl-3-phenylpentanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 75-03-6
ethyl iodide

: 591-51-5
phenyllithium

: 678991-33-8
E-(+)-(1'S,2'S)-N-methyl-N-(2'-phenyl-2'-hydroxy-1'-methylethyl)pent-2-enamide

: (1'S,2'S)-2-ethyl-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N-methyl-3-phenylpentanamide

: 897920-47-7
(+)-(1'S,2'S,2S,3R)-2-ethyl-N-(2'-hydroxy-1'-methyl-2'-phenylethyl)-N-methyl-3-phenylpentanamide

Guidance literature:: phenyllithium; E-(+)-(1'S,2'S)-N-methyl-N-(2'-phenyl-2'-hydroxy-1'-methylethyl)pent-2-enamide; With lithium chloride; In tetrahydrofuran; dibutyl ether; at -105 ℃;

ethyl iodide; In tetrahydrofuran; dibutyl ether; at 0 ℃; for 5h;
DOI:10.1021/ol060720w