Technology Process of 11-(3-(pyridin-2-yloxy)phenoxy)imidazo[1,2-f]phenanthridine
There total 5 articles about 11-(3-(pyridin-2-yloxy)phenoxy)imidazo[1,2-f]phenanthridine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
2-Picolinic acid; copper(l) iodide; potassium phosphate monohydrate;
In
dimethyl sulfoxide;
at 100 ℃;
for 24.5h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium phosphate monohydrate / bis-triphenylphosphine-palladium(II) chloride / toluene; water / 15.5 h / Inert atmosphere
2: sodium hydrogencarbonate / isopropyl alcohol / 15 h / Reflux
3: boron tribromide / dichloromethane / -78 - 20 °C
4: copper(l) iodide; potassium phosphate monohydrate; 2-Picolinic acid / dimethyl sulfoxide / 24.5 h / 100 °C
With
2-Picolinic acid; copper(l) iodide; potassium phosphate monohydrate; boron tribromide; sodium hydrogencarbonate;
bis-triphenylphosphine-palladium(II) chloride;
In
dichloromethane; water; dimethyl sulfoxide; isopropyl alcohol; toluene;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: potassium phosphate monohydrate / bis-triphenylphosphine-palladium(II) chloride / toluene; water / 15.5 h / Inert atmosphere
2: sodium hydrogencarbonate / isopropyl alcohol / 15 h / Reflux
3: boron tribromide / dichloromethane / -78 - 20 °C
4: copper(l) iodide; potassium phosphate monohydrate; 2-Picolinic acid / dimethyl sulfoxide / 24.5 h / 100 °C
With
2-Picolinic acid; copper(l) iodide; potassium phosphate monohydrate; boron tribromide; sodium hydrogencarbonate;
bis-triphenylphosphine-palladium(II) chloride;
In
dichloromethane; water; dimethyl sulfoxide; isopropyl alcohol; toluene;
