(2S,3R)-2-<(benzyloxycarbonyl)amino>-4-(chloroacetoxy)-3-hydroxybutanamide

Base Information

Chemical Name:(2S,3R)-2-<(benzyloxycarbonyl)amino>-4-(chloroacetoxy)-3-hydroxybutanamide
CAS No.:92973-23-4
Molecular Formula:C₁₄H₁₇ClN₂O₆
Molecular Weight:344.752
Hs Code.:

Synonyms:(2S,3R)-2-<(benzyloxycarbonyl)amino>-4-(chloroacetoxy)-3-hydroxybutanamide

Suppliers and Price of (2S,3R)-2-<(benzyloxycarbonyl)amino>-4-(chloroacetoxy)-3-hydroxybutanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R)-2-<(benzyloxycarbonyl)amino>-4-(chloroacetoxy)-3-hydroxybutanamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R)-2-<(benzyloxycarbonyl)amino>-4-(chloroacetoxy)-3-hydroxybutanamide

There total 9 articles about (2S,3R)-2-<(benzyloxycarbonyl)amino>-4-(chloroacetoxy)-3-hydroxybutanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 117069-23-5
(2S,3R)-2-<(benzyloxycarbonyl)amino>-4-hydroxy-3-(mesyloxy)butanamide

: 79-04-9
chloroacetyl chloride

: 92973-23-4
(2S,3R)-2-<(benzyloxycarbonyl)amino>-4-(chloroacetoxy)-3-hydroxybutanamide

Guidance literature:: With N,N-dimethyl acetamide; at -20 ℃;
DOI:10.1021/jo00258a020

Reference yield: 76.0%

: 92754-76-2
(2S,3R)-2-<(benzyloxycarbonyl)amino>-3,4-dihydroxybutanamide

: 79-04-9
chloroacetyl chloride

: 92973-23-4
(2S,3R)-2-<(benzyloxycarbonyl)amino>-4-(chloroacetoxy)-3-hydroxybutanamide

Guidance literature:: With 2,6-dimethylpyridine; In dichloromethane; N,N-dimethyl-formamide; at -10 - 0 ℃; for 1.5h;
DOI:10.1021/jo00219a009

Reference yield:

: 92754-75-1
(2S,3R)-2-<(benzyloxycarbonyl)amino>-3-hydroxy-4-butanolide

: 92973-23-4
(2S,3R)-2-<(benzyloxycarbonyl)amino>-4-(chloroacetoxy)-3-hydroxybutanamide

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / 25-28 percent ammonia/water / hexane / 3 h / 0 - 5 °C

2: 9.31 percent / N,N-dimethyl-acetamide / 1 h / -25 - -20 °C

With ammonium hydroxide; water; In hexane; N,N-dimethyl acetamide;
DOI:10.1248/cpb.33.3798