Quinoline, 7-fluoro-4-methyl- (9CI)

Base Information

• Chemical Name: Quinoline, 7-fluoro-4-methyl- (9CI)
• CAS No.: 144147-01-3
• Molecular Formula: C₁₀H₈FN
• Molecular Weight: 161.179
• Mol file: 144147-01-3.mol

Synonyms:7-Fluoro-4-methylquinoline

Chemical Property of Quinoline, 7-fluoro-4-methyl- (9CI)

Chemical Property:

• PSA: 12.89000
• LogP: 2.68230

Purity/Quality:

98.5% ^*data from raw suppliers

7-Fluoro-4-methylquinoline 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Quinoline, 7-fluoro-4-methyl- (9CI)

There total 1 articles about Quinoline, 7-fluoro-4-methyl- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 21.0%

meta-fluoroaniline (372-19-0) + methyl vinyl ketone (78-94-4,25038-87-3) → 7-Fluoro-4-Methylquinoline (144147-01-3)

Guidance literature:

meta-fluoroaniline; methyl vinyl ketone; In ethanol; at 0 - 20 ℃; for 19h;

With iron(III) chloride; zinc(II) chloride; at 70 ℃; for 13h;

DOI:10.1016/S1383-5718(99)00226-0

upstream raw materials:

meta-fluoroaniline

methyl vinyl ketone

Refernces