4-(2,2-difluoro-6-methylbenzo[d]1,3-dioxolen-5-yl)aniline

Base Information Edit

Chemical Name:4-(2,2-difluoro-6-methylbenzo[d]1,3-dioxolen-5-yl)aniline
CAS No.:1431386-76-3
Molecular Formula:C₁₄H₁₁F₂NO₂
Molecular Weight:263.244
Hs Code.:
Mol file:1431386-76-3.mol

Synonyms:4-(2,2-difluoro-6-methylbenzo[d]1,3-dioxolen-5-yl)aniline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(2,2-difluoro-6-methylbenzo[d]1,3-dioxolen-5-yl)aniline Edit

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Technology Process of 4-(2,2-difluoro-6-methylbenzo[d]1,3-dioxolen-5-yl)aniline

There total 1 articles about 4-(2,2-difluoro-6-methylbenzo[d]1,3-dioxolen-5-yl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.5%

: C₁₅H₁₈F₂O₄

: 106-40-1
4-bromo-aniline

: 1431386-76-3
4-(2,2-difluoro-6-methylbenzo[d]1,3-dioxolen-5-yl)aniline

Guidance literature:: With potassium phosphate; bis(di-tert-?butyl(4-?dimethylaminophenyl)?phosphine)?dichloropalladium(II); In 1,4-dioxane; water; acetonitrile; at 80 ℃; for 4h; Inert atmosphere;

Reference yield: 53.6%

: 402-66-4
5-fluoropyridine-3-carboxylic acid

: 1431386-76-3
4-(2,2-difluoro-6-methylbenzo[d]1,3-dioxolen-5-yl)aniline

: 1431386-22-9
N-[4-(2,2-difluoro-6-methylbenzo[d]1,3-dioxolen-5-yl)phenyl](5-fluoro(3-pyridyl))carboxamide

Guidance literature:: 5-fluoropyridine-3-carboxylic acid; With 4-methyl-morpholine; 2-chloro-4,6-dimethoxy-1 ,3,5-triazine; In dichloromethane; at 20 ℃; for 1h;

4-(2,2-difluoro-6-methylbenzo[d]1,3-dioxolen-5-yl)aniline; In dichloromethane; at 20 ℃; for 4h;