(3S,4S)-2,2-dimethylpropionic acid 4-acetoxy-3-hydroxy-6-phenylhex-5(E)-enyl ester

Base Information

Chemical Name:(3S,4S)-2,2-dimethylpropionic acid 4-acetoxy-3-hydroxy-6-phenylhex-5(E)-enyl ester
CAS No.:178977-55-4
Molecular Formula:C₁₉H₂₆O₅
Molecular Weight:334.412
Hs Code.:

Synonyms:(3S,4S)-2,2-dimethylpropionic acid 4-acetoxy-3-hydroxy-6-phenylhex-5(E)-enyl ester

Suppliers and Price of (3S,4S)-2,2-dimethylpropionic acid 4-acetoxy-3-hydroxy-6-phenylhex-5(E)-enyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (3S,4S)-2,2-dimethylpropionic acid 4-acetoxy-3-hydroxy-6-phenylhex-5(E)-enyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S,4S)-2,2-dimethylpropionic acid 4-acetoxy-3-hydroxy-6-phenylhex-5(E)-enyl ester

There total 7 articles about (3S,4S)-2,2-dimethylpropionic acid 4-acetoxy-3-hydroxy-6-phenylhex-5(E)-enyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1054658-49-9
2,2-Dimethyl-propionic acid (E)-(3S,4S)-4-acetoxy-6-phenyl-3-(tetrahydro-pyran-2-yloxy)-hex-5-enyl ester

: 178977-55-4
(3S,4S)-2,2-dimethylpropionic acid 4-acetoxy-3-hydroxy-6-phenylhex-5(E)-enyl ester

Guidance literature:: With acetic acid; for 3h; Ambient temperature;
DOI:10.1021/jo960816b

Reference yield:

: (3S)-3,4-dihydroxy-6-phenylhex-5-ynoic acid

: 178977-55-4
(3S,4S)-2,2-dimethylpropionic acid 4-acetoxy-3-hydroxy-6-phenylhex-5(E)-enyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 43 percent / p-toluenesulfonic acid / benzene / 1.5 h / 50 °C

2: 1.) p-toluenesulfonic acid, 2.) LiAlH₄ / 1.) THF, room temp., 3 h, 2.) Et₂O, room temp., overnight

3: 1.) pyridine, DMAP / 1.) CH₂Cl₂, 0 deg C, 3 h, 2.) CH₂Cl₂, 3 h

4: 98 percent / aq. AcOH / 3 h / Ambient temperature

With pyridine; dmap; lithium aluminium tetrahydride; toluene-4-sulfonic acid; acetic acid; In benzene;
DOI:10.1021/jo960816b

Reference yield:

: 4440-01-1
lithium phenylacetylide

: 178977-55-4
(3S,4S)-2,2-dimethylpropionic acid 4-acetoxy-3-hydroxy-6-phenylhex-5(E)-enyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: 2.) NaBH₄ / 1.) THF, -78 deg C, 35 min, 2.) THF, EtOH, -78 deg C , 15 min

2: 43 percent / p-toluenesulfonic acid / benzene / 1.5 h / 50 °C

3: 1.) p-toluenesulfonic acid, 2.) LiAlH₄ / 1.) THF, room temp., 3 h, 2.) Et₂O, room temp., overnight

4: 1.) pyridine, DMAP / 1.) CH₂Cl₂, 0 deg C, 3 h, 2.) CH₂Cl₂, 3 h

5: 98 percent / aq. AcOH / 3 h / Ambient temperature

With pyridine; dmap; sodium tetrahydroborate; lithium aluminium tetrahydride; toluene-4-sulfonic acid; acetic acid; In benzene;
DOI:10.1021/jo960816b