5-((2-hydroxy-6-oxo-1-cyclohexen-1-yl)carbonyl)-2,3-diphenyl-4(3H)-pyrimidinone

Base Information

Chemical Name:5-((2-hydroxy-6-oxo-1-cyclohexen-1-yl)carbonyl)-2,3-diphenyl-4(3H)-pyrimidinone
CAS No.:1269997-76-3
Molecular Formula:C₂₃H₁₈N₂O₄
Molecular Weight:386.407
Hs Code.:

Synonyms:5-((2-hydroxy-6-oxo-1-cyclohexen-1-yl)carbonyl)-2,3-diphenyl-4(3H)-pyrimidinone

Suppliers and Price of 5-((2-hydroxy-6-oxo-1-cyclohexen-1-yl)carbonyl)-2,3-diphenyl-4(3H)-pyrimidinone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-((2-hydroxy-6-oxo-1-cyclohexen-1-yl)carbonyl)-2,3-diphenyl-4(3H)-pyrimidinone

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 5-((2-hydroxy-6-oxo-1-cyclohexen-1-yl)carbonyl)-2,3-diphenyl-4(3H)-pyrimidinone

There total 6 articles about 5-((2-hydroxy-6-oxo-1-cyclohexen-1-yl)carbonyl)-2,3-diphenyl-4(3H)-pyrimidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1270000-54-8
3-oxo-1-cyclohexen-1-yl 1,6-dihydro-6-oxo-1,2-diphenyl-5-pyrimidinecarboxylate

: 1269997-76-3
5-((2-hydroxy-6-oxo-1-cyclohexen-1-yl)carbonyl)-2,3-diphenyl-4(3H)-pyrimidinone

Guidance literature:: With triethylamine; 2-hydroxy-2-methylpropanenitrile; In acetonitrile; at 20 ℃; for 24h;

Reference yield:

: 100-47-0
benzonitrile

: 1269997-76-3
5-((2-hydroxy-6-oxo-1-cyclohexen-1-yl)carbonyl)-2,3-diphenyl-4(3H)-pyrimidinone

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium hexamethyldisilazane / tetrahydrofuran / 0.17 h / 20 °C

1.2: 1 h / 20 °C

2.1: ammonium chloride / acetonitrile / 2 h / Reflux

3.1: pyridine; lithium iodide / 24 h / Reflux

3.2: pH 7

4.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 0 - 20 °C

4.2: 0.5 h / 20 °C

5.1: triethylamine / 2-hydroxy-2-methylpropanenitrile / acetonitrile / 24 h / 20 °C

With pyridine; oxalyl dichloride; sodium hexamethyldisilazane; ammonium chloride; triethylamine; lithium iodide; N,N-dimethyl-formamide; 2-hydroxy-2-methylpropanenitrile; In tetrahydrofuran; dichloromethane; acetonitrile;

Reference yield:

: N-phenylbenzenecarboximidamide, sodium salt

: 1269997-76-3
5-((2-hydroxy-6-oxo-1-cyclohexen-1-yl)carbonyl)-2,3-diphenyl-4(3H)-pyrimidinone

Guidance literature:: Multi-step reaction with 4 steps

1.1: ammonium chloride / acetonitrile / 2 h / Reflux

2.1: pyridine; lithium iodide / 24 h / Reflux

2.2: pH 7

3.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 0 - 20 °C

3.2: 0.5 h / 20 °C

4.1: triethylamine / 2-hydroxy-2-methylpropanenitrile / acetonitrile / 24 h / 20 °C

With pyridine; oxalyl dichloride; ammonium chloride; triethylamine; lithium iodide; N,N-dimethyl-formamide; 2-hydroxy-2-methylpropanenitrile; In dichloromethane; acetonitrile;