Cyclobutanecarbonyl chloride, 3-ethyl-, trans- (9CI)

Base Information

• Chemical Name: Cyclobutanecarbonyl chloride, 3-ethyl-, trans- (9CI)
• CAS No.: 143610-61-1
• Molecular Formula: C₇H₁₁ClO
• Molecular Weight: 146.617
• Mol file: 143610-61-1.mol

Synonyms:Cyclobutanecarbonyl chloride, 3-ethyl-, trans- (9CI)

Chemical Property of Cyclobutanecarbonyl chloride, 3-ethyl-, trans- (9CI)

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclobutanecarbonyl chloride, 3-ethyl-, trans- (9CI)

There total 6 articles about Cyclobutanecarbonyl chloride, 3-ethyl-, trans- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.5%

→ 3-ethylcyclobutanecarboxylic acid chloride (76730-61-5,143610-61-1)

Guidance literature:

Reference yield:

3-ethylcyclobutane carboxylic acid (66016-16-8) → 3-ethylcyclobutanecarboxylic acid chloride (76730-61-5,143610-61-1)

Guidance literature:

With thionyl chloride;

Reference yield:

2-ethyl-1,3-propandiol (2612-29-5) → 3-ethylcyclobutanecarboxylic acid chloride (76730-61-5,143610-61-1)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine

2: NaH / dioxane

3: 1.) KOH / 1.) EtOH, H₂O; 2.) reflux

4: thionyl chloride

With pyridine; potassium hydroxide; thionyl chloride; sodium hydride; In 1,4-dioxane;

upstream raw materials:

3-ethylcyclobutane carboxylic acid

2-ethyl-1,3-propandiol

1,1-bis(ethoxycarbonyl)-3-ethyl cyclobutane

2-ethylpropane-1,3-diol di-p-toluenesulphonate

Refernces

• 1、 Chan, L. K. M.,Gemmell, P. A.,Gray, G. W.,Lacey, D.,Toyne, K. J.. "Synthesis and Liquid Crystal Properties of Dimethylene Linked Compounds Incorporating the Cyclobutane or Spiroheptane Rings". . p. 229 - 246. Retrieved 2007/10/02.