(1,3,3-Trimethyl-2-methylideneindol-6-YL)methanol

Base Information

Chemical Name:(1,3,3-Trimethyl-2-methylideneindol-6-YL)methanol
CAS No.:143445-60-7
Molecular Formula:C₁₃H₁₇NO
Molecular Weight:203.284
Hs Code.:
DSSTox Substance ID:DTXSID40434143
Wikidata:Q82248475
Mol file:143445-60-7.mol

Synonyms:143445-60-7;(1,3,3-TRIMETHYL-2-METHYLIDENEINDOL-6-YL)METHANOL;(1,3,3-TRIMETHYL-2-METHYLENE-2,3-DIHYDRO-1H-INDOL-6-YL)-METHANOL;SCHEMBL13619868;DTXSID40434143;AKOS015964100;(1,3,3-Trimethyl-2-methyleneindolin-6-yl)methanol;(1,3,3-Trimethyl-2-methylidene-2,3-dihydro-1H-indol-6-yl)methanol

Suppliers and Price of (1,3,3-Trimethyl-2-methylideneindol-6-YL)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(1,3,3-TRIMETHYL-2-METHYLENE-2,3-DIHYDRO-1H-INDOL-6-YL)-METHANOL 95.00%
5MG
$ 504.63

Total 0 raw suppliers

Chemical Property of (1,3,3-Trimethyl-2-methylideneindol-6-YL)methanol

Chemical Property:

PSA：23.47000
LogP:2.48500
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:203.131014166
Heavy Atom Count:15
Complexity:272

Purity/Quality:: (1,3,3-TRIMETHYL-2-METHYLENE-2,3-DIHYDRO-1H-INDOL-6-YL)-METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(C(=C)N(C2=C1C=CC(=C2)CO)C)C

Technology Process of (1,3,3-Trimethyl-2-methylideneindol-6-YL)methanol

There total 4 articles about (1,3,3-Trimethyl-2-methylideneindol-6-YL)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 143445-59-4
6-(hydroxymethyl)-2,3,3-trimethyl-3H-indole

: 74-88-4
methyl iodide

: 143445-60-7
(1,3,3-Trimethyl-2-methylene-2,3-dihydro-1H-indol-6-yl)-methanol

Guidance literature:: With sodium hydroxide; Yield given. Multistep reaction; 1) ether, reflux, 12 h, 2) H₂O;
DOI:10.1021/jo00046a019

Reference yield:

: 1877-77-6
3-aminobenzenemethanol

: 143445-60-7
(1,3,3-Trimethyl-2-methylene-2,3-dihydro-1H-indol-6-yl)-methanol

Guidance literature:: Multi-step reaction with 3 steps

1.1: HCl; NaNO₂; SnCl₂*2H₂O / H₂O / 0.5 h / 0 °C

2.1: 131 mg / H₂SO₄ / 17 h / Heating

3.1: CH₂Cl₂ / 12 h / Heating

3.2: NaOH / H₂O / 0.25 h

With hydrogenchloride; sulfuric acid; tin(ll) chloride; sodium nitrite; In dichloromethane; water;
DOI:10.1021/jo048207o

Reference yield:

: 143445-58-3
m-(hydroxymethyl)phenylhydrazine

: 143445-60-7
(1,3,3-Trimethyl-2-methylene-2,3-dihydro-1H-indol-6-yl)-methanol

Guidance literature:: Multi-step reaction with 2 steps

1.1: 131 mg / H₂SO₄ / 17 h / Heating

2.1: CH₂Cl₂ / 12 h / Heating

2.2: NaOH / H₂O / 0.25 h

With sulfuric acid; In dichloromethane;
DOI:10.1021/jo048207o