4-chloro-1-[5-(4-chlorobenzoyl)-1-methyl-1H-pyrrol-3-yl]-butanone

Base Information

• Chemical Name: 4-chloro-1-[5-(4-chlorobenzoyl)-1-methyl-1H-pyrrol-3-yl]-butanone
• CAS No.: 157847-13-7
• Molecular Formula: C₁₆H₁₅Cl₂NO₂
• Molecular Weight: 324.207
• Mol file: 157847-13-7.mol

Synonyms:4-chloro-1-[5-(4-chlorobenzoyl)-1-methyl-1H-pyrrol-3-yl]-butanone

Chemical Property of 4-chloro-1-[5-(4-chlorobenzoyl)-1-methyl-1H-pyrrol-3-yl]-butanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 4-chloro-1-[5-(4-chlorobenzoyl)-1-methyl-1H-pyrrol-3-yl]-butanone

There total 3 articles about 4-chloro-1-[5-(4-chlorobenzoyl)-1-methyl-1H-pyrrol-3-yl]-butanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

(4-chlorophenyl)(1-methyl-1H-pyrrol-2-yl)methanone (62128-32-9) + 4-Chlorobutanoyl chloride (4635-59-0) → 4-chloro-1-[5-(4-chlorobenzoyl)-1-methyl-1H-pyrrol-3-yl]-butanone (157847-13-7)

Guidance literature:

With aluminium trichloride; In 1,2-dichloro-ethane; Ambient temperature;

DOI:10.1021/jm9606655

Reference yield:

N-Methylpyrrole (96-54-8) → 4-chloro-1-[5-(4-chlorobenzoyl)-1-methyl-1H-pyrrol-3-yl]-butanone (157847-13-7)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene / Heating

2: 39 percent / AlCl₃ / 1,2-dichloro-ethane / Ambient temperature

With aluminium trichloride; In 1,2-dichloro-ethane; toluene;

DOI:10.1021/jm9606655

Reference yield:

4-chloro-benzoyl chloride (122-01-0) → 4-chloro-1-[5-(4-chlorobenzoyl)-1-methyl-1H-pyrrol-3-yl]-butanone (157847-13-7)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene / Heating

2: 39 percent / AlCl₃ / 1,2-dichloro-ethane / Ambient temperature

With aluminium trichloride; In 1,2-dichloro-ethane; toluene;

DOI:10.1021/jm9606655

upstream raw materials:

(4-chlorophenyl)(1-methyl-1H-pyrrol-2-yl)methanone

4-Chlorobutanoyl chloride

N-Methylpyrrole

4-chloro-benzoyl chloride

Downstream raw materials:

2-[(bis-formyl)amino]-1-[5-(4-chlorobenzoyl)-1-methyl-1-H-pyrrol-3-yl]-ethanone