2-acetyl-1,1,5-trichloro-3-phenyl-1a,2,3,7b-tetrahydro-1H-cyclopropisoquinoline

Base Information

Chemical Name:2-acetyl-1,1,5-trichloro-3-phenyl-1a,2,3,7b-tetrahydro-1H-cyclopropisoquinoline
CAS No.:104576-35-4
Molecular Formula:C₁₈H₁₄Cl₃NO
Molecular Weight:366.674
Hs Code.:

2-acetyl-1,1,5-trichloro-3-phenyl-1a,2,3,7b-tetrahydro-1H-cycloprop<c>isoquinoline

Synonyms:2-acetyl-1,1,5-trichloro-3-phenyl-1a,2,3,7b-tetrahydro-1H-cyclopropisoquinoline

Suppliers and Price of 2-acetyl-1,1,5-trichloro-3-phenyl-1a,2,3,7b-tetrahydro-1H-cyclopropisoquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-acetyl-1,1,5-trichloro-3-phenyl-1a,2,3,7b-tetrahydro-1H-cyclopropisoquinoline

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-acetyl-1,1,5-trichloro-3-phenyl-1a,2,3,7b-tetrahydro-1H-cyclopropisoquinoline

There total 3 articles about 2-acetyl-1,1,5-trichloro-3-phenyl-1a,2,3,7b-tetrahydro-1H-cyclopropisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 67-66-3,8013-54-5
chloroform

: 104576-33-2
N-acetyl-7-chloro-1-phenyl-1,2-dihydroisoquinoline

: 104576-35-4
2-acetyl-1,1,5-trichloro-3-phenyl-1a,2,3,7b-tetrahydro-1H-cyclopropisoquinoline

Guidance literature:: With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; for 4h;
DOI:10.1021/jo00372a009

Reference yield:

: 3418-95-9
1-(benzoylamino)-2-(4-chlorophenyl)ethane

: 104576-35-4
2-acetyl-1,1,5-trichloro-3-phenyl-1a,2,3,7b-tetrahydro-1H-cyclopropisoquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: 40 percent / P₂O₅, POCl₃ / xylene / 6 h / Heating

2: 58 percent / AcOK / 6 h / Heating

3: 55 percent / 40percent aq. NaOH / benzyltriethyl ammonium chloride / 4 h

With sodium hydroxide; potassium acetate; phosphorus pentoxide; trichlorophosphate; N-benzyl-N,N,N-triethylammonium chloride; In xylene;
DOI:10.1021/jo00372a009

Reference yield:

: 104576-30-9
1-phenyl-7-chloro-3,4-dihydroisoquinoline

: 104576-35-4
2-acetyl-1,1,5-trichloro-3-phenyl-1a,2,3,7b-tetrahydro-1H-cyclopropisoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 58 percent / AcOK / 6 h / Heating

2: 55 percent / 40percent aq. NaOH / benzyltriethyl ammonium chloride / 4 h

With sodium hydroxide; potassium acetate; N-benzyl-N,N,N-triethylammonium chloride;
DOI:10.1021/jo00372a009