[2-(bispyridin-2-ylmethylamino)-1-(3,4-dimethoxyphenyl)ethyl]-carbamicacid tert-butyl ester

Base Information

Chemical Name:[2-(bispyridin-2-ylmethylamino)-1-(3,4-dimethoxyphenyl)ethyl]-carbamicacid tert-butyl ester
CAS No.:1297302-47-6
Molecular Formula:C₂₇H₃₄N₄O₄
Molecular Weight:478.591
Hs Code.:

Synonyms:[2-(bispyridin-2-ylmethylamino)-1-(3,4-dimethoxyphenyl)ethyl]-carbamicacid tert-butyl ester

Suppliers and Price of [2-(bispyridin-2-ylmethylamino)-1-(3,4-dimethoxyphenyl)ethyl]-carbamicacid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of [2-(bispyridin-2-ylmethylamino)-1-(3,4-dimethoxyphenyl)ethyl]-carbamicacid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [2-(bispyridin-2-ylmethylamino)-1-(3,4-dimethoxyphenyl)ethyl]-carbamicacid tert-butyl ester

There total 6 articles about [2-(bispyridin-2-ylmethylamino)-1-(3,4-dimethoxyphenyl)ethyl]-carbamicacid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.1%

: 1181816-80-7
[1-(3,4-dimethoxyphenyl)-2-oxo-ethyl]-carbamicacid tert-butyl ester

: 1539-42-0
bis[(2-pyridyl)methyl]amine

: 1297302-47-6
[2-(bispyridin-2-ylmethylamino)-1-(3,4-dimethoxyphenyl)ethyl]-carbamicacid tert-butyl ester

Guidance literature:: With sodium tris(acetoxy)borohydride; acetic acid; In dichloromethane; at 23 ℃; for 24h;
DOI:10.1002/chem.201001982

Reference yield:

: 1297302-53-4
1-(3,4-dimethoxyphenyl)-N,N,N',N'-tetrakispyridin-2-ylmethyl-ethane-1,2-diamine

: 1297302-47-6
[2-(bispyridin-2-ylmethylamino)-1-(3,4-dimethoxyphenyl)ethyl]-carbamicacid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: trifluorormethanesulfonic acid; nitric acid / dichloromethane / 10 h / -42 °C

2: water; dimethyl sulfoxide; zinc(II) chloride; 9-(o-carboxyphenyl)-2,7-dichloro-4,5-bis[bis(2-pyridylmethyl)-aminomethyl]-6-hydroxy-3-xanthanone / 0.07 h / pH 7.4 / Irradiation

3: sodium tris(acetoxy)borohydride; acetic acid / dichloromethane / 24 h / 23 °C

With trifluorormethanesulfonic acid; water; nitric acid; sodium tris(acetoxy)borohydride; acetic acid; dimethyl sulfoxide; zinc(II) chloride; 9-(o-carboxyphenyl)-2,7-dichloro-4,5-bis[bis(2-pyridylmethyl)-aminomethyl]-6-hydroxy-3-xanthanone; In dichloromethane;
DOI:10.1002/chem.201001982

Reference yield:

: C₂₈H₃₁N₅O₂

: 1297302-47-6
[2-(bispyridin-2-ylmethylamino)-1-(3,4-dimethoxyphenyl)ethyl]-carbamicacid tert-butyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: sodium tris(acetoxy)borohydride / dichloromethane / 24 h / 23 °C

2: trifluorormethanesulfonic acid; nitric acid / dichloromethane / 10 h / -42 °C

3: water; dimethyl sulfoxide; zinc(II) chloride; 9-(o-carboxyphenyl)-2,7-dichloro-4,5-bis[bis(2-pyridylmethyl)-aminomethyl]-6-hydroxy-3-xanthanone / 0.07 h / pH 7.4 / Irradiation

4: sodium tris(acetoxy)borohydride; acetic acid / dichloromethane / 24 h / 23 °C

With trifluorormethanesulfonic acid; water; nitric acid; sodium tris(acetoxy)borohydride; acetic acid; dimethyl sulfoxide; zinc(II) chloride; 9-(o-carboxyphenyl)-2,7-dichloro-4,5-bis[bis(2-pyridylmethyl)-aminomethyl]-6-hydroxy-3-xanthanone; In dichloromethane;
DOI:10.1002/chem.201001982