(2S)-2-[(tert-butoxycarbonyl)amino]-2-phenylethyl methanesulfonate

Base Information

Chemical Name:(2S)-2-[(tert-butoxycarbonyl)amino]-2-phenylethyl methanesulfonate
CAS No.:110143-62-9
Molecular Formula:C₁₄H₂₁NO₅S
Molecular Weight:315.39
Hs Code.:
UNII:YVA32AE7TW
Nikkaji Number:J1.770.404D

Synonyms:110143-62-9;TERT-BUTYL N-[(1S)-2-(METHANESULFONYLOXY)-1-PHENYLETHYL]CARBAMATE;(2S)-2-[(tert-butoxycarbonyl)amino]-2-phenylethyl methanesulfonate;(S)-2-Phenyl-2-tert-butoxycarbonylaminoethyl methanesulfonate;(S)-2-((tert-butoxycarbonyl)amino)-2-phenylethyl methanesulfonate;[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-2-phenylethyl] methanesulfonate;YVA32AE7TW;SCHEMBL669317;QMCZMSKKAHWYBJ-GFCCVEGCSA-N;BS-35288;CS-0210745;D85928;(2S)-2-[(tert-Butoxycabonyl)amino]-2-phenylethyl methanesulfonate;[(1S)-1-Phenyl-2-(mesyloxy)ethyl]carbamic acid tert-butyl ester;1,1-Dimethylethyl N-[(1S)-2-[(methylsulfonyl)oxy]-1-phenylethyl]carbamate;2-tert-Butoxycarbonylamino-1-methanesulfonyloxy-2-phenylethane, (S)-;TERT-BUTYLN-[(1S)-2-(METHANESULFONYLOXY)-1-PHENYLETHYL]CARBAMATE;Carbamic acid, [2-[(methylsulfonyl)oxy]-1-phenylethyl]-, 1,1-dimethylethyl ester, (S)-;Carbamic acid, N-[(1S)-2-[(methylsulfonyl)oxy]-1-phenylethyl]-, 1,1-dimethylethyl ester

Suppliers and Price of (2S)-2-[(tert-butoxycarbonyl)amino]-2-phenylethyl methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (2S)-2-[(tert-butoxycarbonyl)amino]-2-phenylethyl methanesulfonate

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:315.11404394
Heavy Atom Count:21
Complexity:429

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(COS(=O)(=O)C)C1=CC=CC=C1
Isomeric SMILES:CC(C)(C)OC(=O)N[C@H](COS(=O)(=O)C)C1=CC=CC=C1

Technology Process of (2S)-2-[(tert-butoxycarbonyl)amino]-2-phenylethyl methanesulfonate

There total 8 articles about (2S)-2-[(tert-butoxycarbonyl)amino]-2-phenylethyl methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 117049-14-6
tert-butyl N-[(1S)-2-hydroxy-1-phenylethyl]carbamate

: 124-63-0
methanesulfonyl chloride

: 110143-62-9
(S)-(+)-<2-<(methylsulfonyl)oxy>-1-phenylethyl>carbamic acid 1,1-dimethylethyl ester

Guidance literature:: With triethylamine; In dichloromethane; at -5 ℃; for 2h; Inert atmosphere;

Reference yield: 91.0%

: 2900-27-8
(2S)-2-[(tert-butoxycarbonyl)amino]-2-phenylethanoic acid

: 124-63-0
methanesulfonyl chloride

: 110143-62-9
(S)-(+)-<2-<(methylsulfonyl)oxy>-1-phenylethyl>carbamic acid 1,1-dimethylethyl ester

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 0 - 10 ℃;

Reference yield:

: 2900-27-8
(2S)-2-[(tert-butoxycarbonyl)amino]-2-phenylethanoic acid

: 110143-62-9
(S)-(+)-<2-<(methylsulfonyl)oxy>-1-phenylethyl>carbamic acid 1,1-dimethylethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran

2: triethylamine / dichloromethane

With triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1039/c2ob25693b