N-<3-<2-(dimethylamino)ethoxy>-4-methoxyphenyl>aminoacetaldehyde dimethyl acetal

Base Information

• Chemical Name: N-<3-<2-(dimethylamino)ethoxy>-4-methoxyphenyl>aminoacetaldehyde dimethyl acetal
• CAS No.: 170691-24-4
• Molecular Formula: C₁₅H₂₆N₂O₄
• Molecular Weight: 298.382
• Mol file: 170691-24-4.mol

Synonyms:N-<3-<2-(dimethylamino)ethoxy>-4-methoxyphenyl>aminoacetaldehyde dimethyl acetal

Chemical Property of N-<3-<2-(dimethylamino)ethoxy>-4-methoxyphenyl>aminoacetaldehyde dimethyl acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-<3-<2-(dimethylamino)ethoxy>-4-methoxyphenyl>aminoacetaldehyde dimethyl acetal

There total 3 articles about N-<3-<2-(dimethylamino)ethoxy>-4-methoxyphenyl>aminoacetaldehyde dimethyl acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-nitroguaiacol (636-93-1) → N-<3-<2-(dimethylamino)ethoxy>-4-methoxyphenyl>aminoacetaldehyde dimethyl acetal (170691-24-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 70 percent / K₂CO₃ / acetone; H₂O / 10 h / Heating

2: 95 percent / H₂ / 10 percent Pd/C / ethanol / Ambient temperature

3: 2.) H₂ / 2.) 10 percent Pd/C / 1.) MeOtBu, EtOH, RT, 16 h, 2.) MeOtBu, EtOH, RT, 7 h

With hydrogen; potassium carbonate; palladium on activated charcoal; In ethanol; water; acetone;

DOI:10.1021/jm970457s

Reference yield:

3-<2-(dimethylamino)ethoxy>-4-nitroanisole (170229-67-1) → N-<3-<2-(dimethylamino)ethoxy>-4-methoxyphenyl>aminoacetaldehyde dimethyl acetal (170691-24-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / H₂ / 10 percent Pd/C / ethanol / Ambient temperature

2: 2.) H₂ / 2.) 10 percent Pd/C / 1.) MeOtBu, EtOH, RT, 16 h, 2.) MeOtBu, EtOH, RT, 7 h

With hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1021/jm970457s

Reference yield:

dimethoxyacetaldehyde (51673-84-8) + 3-[2-(dimethylamino)ethoxy]-4-methoxyaniline (170229-68-2) → N-<3-<2-(dimethylamino)ethoxy>-4-methoxyphenyl>aminoacetaldehyde dimethyl acetal (170691-24-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; Yield given; Multistep reaction; 1.) MeOtBu, EtOH, RT, 16 h, 2.) MeOtBu, EtOH, RT, 7 h;

DOI:10.1021/jm970457s

upstream raw materials:

dimethoxyacetaldehyde

3-[2-(dimethylamino)ethoxy]-4-methoxyaniline

5-nitroguaiacol

3-<2-(dimethylamino)ethoxy>-4-nitroanisole