5-Methoxy-2-(1H-pyrazol-1-YL)benzoic acid

Base Information

Chemical Name:5-Methoxy-2-(1H-pyrazol-1-YL)benzoic acid
CAS No.:1214622-45-3
Molecular Formula:C₁₁H₁₀N₂O₃
Molecular Weight:218.212
Hs Code.:
DSSTox Substance ID:DTXSID101269999

Synonyms:5-METHOXY-2-(1H-PYRAZOL-1-YL)BENZOIC ACID;1214622-45-3;5-methoxy-2-pyrazol-1-ylbenzoic acid;SCHEMBL16464646;DTXSID101269999;AKOS015851696;5-METHOXY-2-(1H-PYRAZOL-1-YL)BENZOICACID

Suppliers and Price of 5-Methoxy-2-(1H-pyrazol-1-YL)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
5-Methoxy-2-(1H-pyrazol-1-yl)benzoic acid
2.500g
$ 720.00

Matrix Scientific
5-Methoxy-2-(1H-pyrazol-1-yl)benzoic acid
500mg
$ 237.00

American Custom Chemicals Corporation
5-METHOXY-2-(1H-PYRAZOL-1-YL)BENZOIC ACID 95.00%
500MG
$ 837.38

Total 2 raw suppliers

Chemical Property of 5-Methoxy-2-(1H-pyrazol-1-YL)benzoic acid

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:218.06914219
Heavy Atom Count:16
Complexity:260

Purity/Quality:

98%min ^*data from raw suppliers

5-Methoxy-2-(1H-pyrazol-1-yl)benzoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)N2C=CC=N2)C(=O)O

Technology Process of 5-Methoxy-2-(1H-pyrazol-1-YL)benzoic acid

There total 3 articles about 5-Methoxy-2-(1H-pyrazol-1-YL)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 102-52-3
malonaldehydebis(dimethylacetal)

: 5-methoxy-2-hydrazinobenzoic acid dihydrochloride

: 1214622-45-3
5-methoxy-2-(1H-pyrazol-1-yl)benzoic acid

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; water; at 20 ℃; for 2h;
DOI:10.1002/chem.201801671

Reference yield:

: 124-38-9,18923-20-1
carbon dioxide

: C₁₆H₂₄N₂OSi

: 1214622-45-3
5-methoxy-2-(1H-pyrazol-1-yl)benzoic acid

Guidance literature:: With cesium fluoride; In N,N-dimethyl-formamide; at 100 ℃; for 16h; under 760.051 Torr;
DOI:10.1055/s-0033-1341230

Reference yield:

: 35715-67-4
1-(4-methoxyphenyl)-1H-pyrazole

: 1214622-45-3
5-methoxy-2-(1H-pyrazol-1-yl)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: norbornene; carbonyl bis(hydrido)tris(triphenylphosphine)ruthenium(II) / toluene / 20 h / 100 °C / Sealed tube; Inert atmosphere

2: cesium fluoride / N,N-dimethyl-formamide / 16 h / 100 °C / 760.05 Torr

With carbonyl bis(hydrido)tris(triphenylphosphine)ruthenium(II); norbornene; cesium fluoride; In N,N-dimethyl-formamide; toluene;
DOI:10.1055/s-0033-1341230