[S-(R*,S*)]-5-(1,5-dimethylhexen-4-yl)-2-methyl-1,3-cyclohexa-1,3-diene

Base Information

• Chemical Name: [S-(R*,S*)]-5-(1,5-dimethylhexen-4-yl)-2-methyl-1,3-cyclohexa-1,3-diene
• CAS No.: 159849-08-8
• Molecular Formula: C₁₅H₂₄
• Molecular Weight: 204.356
• Mol file: 159849-08-8.mol

Synonyms:[S-(R*,S*)]-5-(1,5-dimethylhexen-4-yl)-2-methyl-1,3-cyclohexa-1,3-diene

Chemical Property of [S-(R*,S*)]-5-(1,5-dimethylhexen-4-yl)-2-methyl-1,3-cyclohexa-1,3-diene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [S-(R*,S*)]-5-(1,5-dimethylhexen-4-yl)-2-methyl-1,3-cyclohexa-1,3-diene

There total 7 articles about [S-(R*,S*)]-5-(1,5-dimethylhexen-4-yl)-2-methyl-1,3-cyclohexa-1,3-diene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

(3R,6S,7R)-1,10-bisaboladien-3-ol (72346-44-2) → [S-(R*,S*)]-3-(1,5-dimethyl-4-hexenyl)-6-methylene-cyclohexene + [S-(R*,S*)]-5-(1,5-dimethylhexen-4-yl)-2-methyl-1,3-cyclohexa-1,3-diene (159849-08-8)

Guidance literature:

With pyridine; trichlorophosphate; at 0 - 25 ℃;

DOI:10.1021/np5003753

Reference yield: 36.0%

(3S,6S,7R)-1,10-bisaboladien-3-ol (72346-45-3) → [S-(R*,S*)]-3-(1,5-dimethyl-4-hexenyl)-6-methylene-cyclohexene + [S-(R*,S*)]-5-(1,5-dimethylhexen-4-yl)-2-methyl-1,3-cyclohexa-1,3-diene (159849-08-8)

Guidance literature:

With pyridine; trichlorophosphate; at 0 - 25 ℃;

DOI:10.1021/np5003753

Reference yield:

methyl magnesium iodide (917-64-6) + 4-[(1R)-1,5-dimethylhex-4-enyl]cyclohex-2-en-1-one (196193-23-4) → [S-(R*,S*)]-5-(1,5-dimethylhexen-4-yl)-2-methyl-1,3-cyclohexa-1,3-diene (159849-08-8)

Guidance literature:

4-[(1R)-1,5-dimethylhex-4-enyl]cyclohex-2-en-1-one; With potassium hexamethylsilazane; In tetrahydrofuran; at -78 ℃; for 3h;

With phenylbis[(trifluoromethyl)sulfonyl]amine; In tetrahydrofuran; at -78 ℃; for 1h;

methyl magnesium iodide; copper(l) iodide; In tetrahydrofuran; diethyl ether; at 0 ℃; for 0.25h; Further stages.;

DOI:10.1002/anie.200701552

upstream raw materials:

methyl magnesium iodide

4-[(1R)-1,5-dimethylhex-4-enyl]cyclohex-2-en-1-one

(R)-Citronellal

(2RS,3R)-3,7-Dimethyl-2-(3-oxobutyl)oct-6-enal

Downstream raw materials:

(24R)-epi-biyouyanagin A

cyclobutane

C₃₁H₃₇FO₄

C₃₂H₄₀O₅