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C18H15F2N5

Base Information
  • Chemical Name:C18H15F2N5
  • CAS No.:1374001-10-1
  • Molecular Formula:C18H15F2N5
  • Molecular Weight:339.347
  • Hs Code.:
C<sub>18</sub>H<sub>15</sub>F<sub>2</sub>N<sub>5</sub>

Synonyms:C18H15F2N5

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Chemical Property of C18H15F2N5
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Technology Process of C18H15F2N5

There total 11 articles about C18H15F2N5 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In water; N,N-dimethyl-formamide; at 100 ℃; for 2h; Inert atmosphere;
Guidance literature:
Multi-step reaction with 11 steps
1.1: tetrahydrofuran / 1 h / -78 - -5 °C / Inert atmosphere
2.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / ethyl acetate / 7 h / Reflux
3.1: titanium(IV) tetraethanolate / tetrahydrofuran / 4.5 h / Inert atmosphere; Reflux
4.1: diethyl ether / 3 h / -78 - 0 °C / Inert atmosphere
5.1: hydrogenchloride / methanol; 1,4-dioxane / 1 h / 20 °C
6.1: tetrahydrofuran / 8 h / 60 °C
7.1: ozone / dichloromethane / -78 °C
7.2: 1 h / -78 - 20 °C / Inert atmosphere
8.1: ammonium bicarbonate / methanol; water / 24 h / 20 °C
9.1: hydrogenchloride / methanol; 1,4-dioxane / 16 h / 20 °C
10.1: acetonitrile / 0.5 h / 20 °C
10.2: 1 h / 80 °C
10.3: 1 h / 20 °C
11.1: sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / water; N,N-dimethyl-formamide / 2 h / 100 °C / Inert atmosphere
With hydrogenchloride; titanium(IV) tetraethanolate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium carbonate; ammonium bicarbonate; ozone; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; 1,4-dioxane; methanol; diethyl ether; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide; acetonitrile;
Guidance literature:
Multi-step reaction with 9 steps
1.1: titanium(IV) tetraethanolate / tetrahydrofuran / 4.5 h / Inert atmosphere; Reflux
2.1: diethyl ether / 3 h / -78 - 0 °C / Inert atmosphere
3.1: hydrogenchloride / methanol; 1,4-dioxane / 1 h / 20 °C
4.1: tetrahydrofuran / 8 h / 60 °C
5.1: ozone / dichloromethane / -78 °C
5.2: 1 h / -78 - 20 °C / Inert atmosphere
6.1: ammonium bicarbonate / methanol; water / 24 h / 20 °C
7.1: hydrogenchloride / methanol; 1,4-dioxane / 16 h / 20 °C
8.1: acetonitrile / 0.5 h / 20 °C
8.2: 1 h / 80 °C
8.3: 1 h / 20 °C
9.1: sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / water; N,N-dimethyl-formamide / 2 h / 100 °C / Inert atmosphere
With hydrogenchloride; titanium(IV) tetraethanolate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium carbonate; ammonium bicarbonate; ozone; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; 1,4-dioxane; methanol; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;
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