N-[2-({4-[3-chloro-4-hydroxyanilino]quinazolin-5-yl}oxy)ethyl]-2-hydroxy-N-methylacetamide

Base Information

Chemical Name:N-[2-({4-[3-chloro-4-hydroxyanilino]quinazolin-5-yl}oxy)ethyl]-2-hydroxy-N-methylacetamide
CAS No.:853001-90-8
Molecular Formula:C₁₉H₁₉ClN₄O₄
Molecular Weight:402.837
Hs Code.:

Synonyms:N-[2-({4-[3-chloro-4-hydroxyanilino]quinazolin-5-yl}oxy)ethyl]-2-hydroxy-N-methylacetamide

Suppliers and Price of N-[2-({4-[3-chloro-4-hydroxyanilino]quinazolin-5-yl}oxy)ethyl]-2-hydroxy-N-methylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[2-({4-[3-chloro-4-hydroxyanilino]quinazolin-5-yl}oxy)ethyl]-2-hydroxy-N-methylacetamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-[2-({4-[3-chloro-4-hydroxyanilino]quinazolin-5-yl}oxy)ethyl]-2-hydroxy-N-methylacetamide

There total 2 articles about N-[2-({4-[3-chloro-4-hydroxyanilino]quinazolin-5-yl}oxy)ethyl]-2-hydroxy-N-methylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 853001-90-8
N-[2-({4-[3-chloro-4-hydroxyanilino]quinazolin-5-yl}oxy)ethyl]-2-hydroxy-N-methylacetamide

Guidance literature:

Reference yield:

: 853001-89-5
2-chloro-4-({5-[2-(methylamino)ethoxy]quinazolin-4-yl}amino)phenol

: 79-14-1
glycolic Acid

: 853001-90-8
N-[2-({4-[3-chloro-4-hydroxyanilino]quinazolin-5-yl}oxy)ethyl]-2-hydroxy-N-methylacetamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃;
DOI:10.1016/j.bmcl.2007.08.073

Reference yield: 54.0%

: 853001-90-8
N-[2-({4-[3-chloro-4-hydroxyanilino]quinazolin-5-yl}oxy)ethyl]-2-hydroxy-N-methylacetamide

: N-(2-{[4-(3-chloro-4-[(6-methylpyridin-2-yl)methoxy]anilino)quinazolin-5-yl]oxy}ethyl)-2-hydroxy-N-methylacetamide

Guidance literature:: 2-(Hydroxymethyl)-6-methylpyridine; With methanesulfonyl chloride; triethylamine; In dichloromethane;

N-[2-({4-[3-chloro-4-hydroxyanilino]quinazolin-5-yl}oxy)ethyl]-2-hydroxy-N-methylacetamide; With potassium carbonate; In DMF (N,N-dimethyl-formamide); for 48h;