3-(3,4-dimethoxy-phenyl)-acrylic acid 3-[4-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-phenyl]-2-oxo-propyl ester

Base Information

Chemical Name:3-(3,4-dimethoxy-phenyl)-acrylic acid 3-[4-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-phenyl]-2-oxo-propyl ester
CAS No.:854737-65-8
Molecular Formula:C₂₇H₃₆O₇Si
Molecular Weight:500.664
Hs Code.:

3-(3,4-dimethoxy-phenyl)-acrylic acid 3-[4-(<i>tert</i>-butyl-dimethyl-silanyloxy)-3-methoxy-phenyl]-2-oxo-propyl ester

Synonyms:3-(3,4-dimethoxy-phenyl)-acrylic acid 3-[4-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-phenyl]-2-oxo-propyl ester

Suppliers and Price of 3-(3,4-dimethoxy-phenyl)-acrylic acid 3-[4-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-phenyl]-2-oxo-propyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(3,4-dimethoxy-phenyl)-acrylic acid 3-[4-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-phenyl]-2-oxo-propyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(3,4-dimethoxy-phenyl)-acrylic acid 3-[4-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-phenyl]-2-oxo-propyl ester

There total 5 articles about 3-(3,4-dimethoxy-phenyl)-acrylic acid 3-[4-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-phenyl]-2-oxo-propyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 854737-55-6
1-bromo-2-keto-3-(3-methoxy-4-t-butyldimethylsilyloxy)phenyl propane

: 14737-89-4
3,4-dimethoxy-trans-cinnamic acid

: 854737-65-8
3-(3,4-dimethoxy-phenyl)-acrylic acid 3-[4-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-phenyl]-2-oxo-propyl ester

Guidance literature:: With sodium hydroxide; tetrabutylammomium bromide; In toluene; at 20 ℃;
DOI:10.1016/j.tet.2005.03.074

Reference yield:

: 854737-56-7
1-bromo-2-hydroxy-3-(3-methoxy-4-t-butyldimethylsilyloxy)phenyl propane

: 854737-65-8
3-(3,4-dimethoxy-phenyl)-acrylic acid 3-[4-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-phenyl]-2-oxo-propyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / Dess-Martin reagent / CH₂Cl₂ / 15 h / 20 °C

2: 41 percent / aq. NaOH; NBu₄Br / toluene / 20 °C

With sodium hydroxide; tetrabutylammomium bromide; Dess-Martin periodane; In dichloromethane; toluene; 1: Dess-Martin oxidation;
DOI:10.1016/j.tet.2005.03.074

Reference yield:

: 97-53-0
4-allylguaiacol

: 854737-65-8
3-(3,4-dimethoxy-phenyl)-acrylic acid 3-[4-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-phenyl]-2-oxo-propyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 90 percent / imidazole; DMAP / CH₂Cl₂ / 0 - 20 °C

2: 78 percent / NBS; H₂O / dimethylsulfoxide / 0 °C

3: 78 percent / Dess-Martin reagent / CH₂Cl₂ / 15 h / 20 °C

4: 41 percent / aq. NaOH; NBu₄Br / toluene / 20 °C

With 1H-imidazole; dmap; sodium hydroxide; N-Bromosuccinimide; tetrabutylammomium bromide; water; Dess-Martin periodane; In dichloromethane; dimethyl sulfoxide; toluene; 3: Dess-Martin oxidation;
DOI:10.1016/j.tet.2005.03.074