(E)-N'-isopropyl-N'-(3-(1-pivaloyl-1H-indol-3-yl)acryloyl)benzohydrazide

Base Information

Chemical Name:(E)-N'-isopropyl-N'-(3-(1-pivaloyl-1H-indol-3-yl)acryloyl)benzohydrazide
CAS No.:1407499-69-7
Molecular Formula:C₂₆H₂₉N₃O₃
Molecular Weight:431.535
Hs Code.:

Synonyms:(E)-N'-isopropyl-N'-(3-(1-pivaloyl-1H-indol-3-yl)acryloyl)benzohydrazide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (E)-N'-isopropyl-N'-(3-(1-pivaloyl-1H-indol-3-yl)acryloyl)benzohydrazide

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Technology Process of (E)-N'-isopropyl-N'-(3-(1-pivaloyl-1H-indol-3-yl)acryloyl)benzohydrazide

There total 5 articles about (E)-N'-isopropyl-N'-(3-(1-pivaloyl-1H-indol-3-yl)acryloyl)benzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

: 1407499-60-8
(E)-N'-(3-(1H-indol-3-yl)acryloyl)-N'-isopropylbenzohydrazide

: 3282-30-2
pivaloyl chloride

: 1407499-69-7
(E)-N'-isopropyl-N'-(3-(1-pivaloyl-1H-indol-3-yl)acryloyl)benzohydrazide

Guidance literature:: With dmap; potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

Reference yield:

: 3408-21-7
1-benzoyl-2-isopropylhydrazine

: 1407499-69-7
(E)-N'-isopropyl-N'-(3-(1-pivaloyl-1H-indol-3-yl)acryloyl)benzohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 12 h / 20 °C

2: potassium carbonate; dmap / N,N-dimethyl-formamide / 24 h / 20 °C

With dmap; potassium carbonate; N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide;

Reference yield:

: 1204-06-4,29953-71-7
trans-3-indole-acrylic acid

: 1407499-69-7
(E)-N'-isopropyl-N'-(3-(1-pivaloyl-1H-indol-3-yl)acryloyl)benzohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 12 h / 20 °C

2: potassium carbonate; dmap / N,N-dimethyl-formamide / 24 h / 20 °C

With dmap; potassium carbonate; N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide;