5-Butoxy-2-hydroxybenzaldehyde

Base Information

• Chemical Name: 5-Butoxy-2-hydroxybenzaldehyde
• CAS No.: 41002-38-4
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.23
• DSSTox Substance ID: DTXSID201305336
• Mol file: 41002-38-4.mol

Synonyms:5-butoxy-2-hydroxybenzaldehyde;41002-38-4;SCHEMBL8415236;DTXSID201305336;AKOS037680105

Chemical Property of 5-Butoxy-2-hydroxybenzaldehyde

Chemical Property:

• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 194.094294304
• Heavy Atom Count: 14
• Complexity: 170

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCCCOC1=CC(=C(C=C1)O)C=O

Technology Process of 5-Butoxy-2-hydroxybenzaldehyde

There total 3 articles about 5-Butoxy-2-hydroxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 4-n-butoxyphenol (122-94-1) → 5-butoxy-2-hydroxy-benzaldehyde (41002-38-4)

Guidance literature:

4-n-butoxyphenol; With magnesium methanolate; In methanol; Reflux;

formaldehyd; In toluene; at 95 ℃; for 1h;

With hydrogenchloride; In water; toluene; at 20 ℃;

DOI:10.1016/j.ejmech.2013.11.035

Reference yield:

4-n-butoxyphenol (122-94-1) → 5-butoxy-2-hydroxy-benzaldehyde (41002-38-4)

Guidance literature:

With hydrogenchloride; sodium hydroxide; In hexane; chloroform; ethyl acetate;

Reference yield:

chloroform (67-66-3,8013-54-5) + 4-n-butoxyphenol (122-94-1) → 5-butoxy-2-hydroxy-benzaldehyde (41002-38-4)

Guidance literature:

With sodium hydroxide; Yield given. Multistep reaction; 1.) 65 deg C, 2.) reflux, 2 h;

DOI:10.1016/0223-5234(96)85165-8

upstream raw materials:

chloroform

4-n-butoxyphenol

formaldehyd

Downstream raw materials:

5-Butoxy-2-(2,2-diethoxy-ethoxy)-benzaldehyde