6-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine

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Chemical Name:6-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine
CAS No.:1361570-11-7
Molecular Formula:C₂₀H₁₇FN₆
Molecular Weight:360.394
Hs Code.:

Synonyms:6-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine

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Chemical Property of 6-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine

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Technology Process of 6-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine

There total 5 articles about 6-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1361569-45-0
6-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrido[2,3-b]pyrazine

: 1361570-11-7
6-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine

Guidance literature:: With platinum(IV) oxide; hydrogen; In methanol;

Reference yield:

: 1313738-72-5
1-(2-fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-b]pyridine

: 1361570-11-7
6-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine

Guidance literature:: Multi-step reaction with 4 steps

1: bis(tri-n-butyltin); dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / N,N-dimethyl-formamide / 110 °C / Inert atmosphere

2: palladium 10% on activated carbon; hydrogen / methanol / 20 °C

3: ethanol / 5 h / 20 °C

4: hydrogen; platinum(IV) oxide / methanol

With platinum(IV) oxide; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; palladium 10% on activated carbon; hydrogen; bis(tri-n-butyltin); In methanol; ethanol; N,N-dimethyl-formamide;

Reference yield:

: 1361570-37-7
6-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-3-nitropyridin-2-amine

: 1361570-11-7
6-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine

Guidance literature:: Multi-step reaction with 3 steps

1: palladium 10% on activated carbon; hydrogen / methanol / 20 °C

2: ethanol / 5 h / 20 °C

3: hydrogen; platinum(IV) oxide / methanol

With platinum(IV) oxide; palladium 10% on activated carbon; hydrogen; In methanol; ethanol;