3-(3-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-5-yl)cyclopentanone

Base Information

Chemical Name:3-(3-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-5-yl)cyclopentanone
CAS No.:1035215-80-5
Molecular Formula:C₁₆H₁₇ClN₂O₃
Molecular Weight:320.776
Hs Code.:

Synonyms:3-(3-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-5-yl)cyclopentanone

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Chemical Property of 3-(3-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-5-yl)cyclopentanone

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Technology Process of 3-(3-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-5-yl)cyclopentanone

There total 1 articles about 3-(3-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-5-yl)cyclopentanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 1035216-81-9,1035218-35-9
(Z)-3-chloro-N'-hydroxy-4-isopropoxybenzimidamide

: 98-78-2
3-Oxo-cyclopentanecarboxylic acid

: 1035215-80-5
3-(3-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-5-yl)cyclopentanone

Guidance literature:: 3-Oxo-cyclopentanecarboxylic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; for 1h;

(Z)-3-chloro-N'-hydroxy-4-isopropoxybenzimidamide; In N,N-dimethyl-formamide; at 140 ℃; for 0.75h;

Reference yield:

: 1035215-80-5
3-(3-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-5-yl)cyclopentanone

: 56-12-2
4-amino-n-butyric acid

: 1035215-84-9
4-(3-(3-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-5-yl)cyclopentylamino)butanoic acid

Guidance literature:: 3-(3-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-5-yl)cyclopentanone; 4-amino-n-butyric acid; With acetic acid; In methanol; DCE; at 20 ℃; for 0.5 - 1h;

With sodium cyanoborohydride; In methanol; DCE; at 20 ℃;

Reference yield:

: 1035215-80-5
3-(3-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-5-yl)cyclopentanone

: 107-95-9
3-amino propanoic acid

: 1035215-82-7
3-(3-(3-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-5-yl)cyclopentylamino)propanoic acid

Guidance literature:: 3-(3-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-5-yl)cyclopentanone; 3-amino propanoic acid; With acetic acid; In methanol; DCE; for 1h;

With sodium cyanoborohydride; In methanol; DCE; for 15h;