(R)-bis(3-fluorophenyl)methyl quinuclidin-3-ylcarbamate

Base Information

Chemical Name:(R)-bis(3-fluorophenyl)methyl quinuclidin-3-ylcarbamate
CAS No.:1404054-16-5
Molecular Formula:C₂₁H₂₂F₂N₂O₂
Molecular Weight:372.415
Hs Code.:

Synonyms:(R)-bis(3-fluorophenyl)methyl quinuclidin-3-ylcarbamate

Suppliers and Price of (R)-bis(3-fluorophenyl)methyl quinuclidin-3-ylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-bis(3-fluorophenyl)methyl quinuclidin-3-ylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-bis(3-fluorophenyl)methyl quinuclidin-3-ylcarbamate

There total 3 articles about (R)-bis(3-fluorophenyl)methyl quinuclidin-3-ylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₁H₁₆N₄O

: 98586-21-1
bis(3-fluorophenyl)methanol

: 1404054-16-5
(R)-bis(3-fluorophenyl)methyl quinuclidin-3-ylcarbamate

Guidance literature:: bis(3-fluorophenyl)methanol; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 0.5h;

C₁₁H₁₆N₄O; In N,N-dimethyl-formamide; at 20 ℃; for 48h;

Reference yield:

: 6530-09-2,119904-90-4,120538-52-5,123536-14-1,124577-62-4,126358-22-3,137661-30-4,137661-31-5
(3R)-quinuclidin-3-amine dihydrochloride

: 98586-21-1
bis(3-fluorophenyl)methanol

: 530-62-1
1,1'-carbonyldiimidazole

: 1404054-16-5
(R)-bis(3-fluorophenyl)methyl quinuclidin-3-ylcarbamate

Guidance literature:: (3R)-quinuclidin-3-amine dihydrochloride; With sodium hydrogencarbonate; In methanol; water; at 20 ℃; for 1h;

1,1'-carbonyldiimidazole; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

bis(3-fluorophenyl)methanol; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 48h;

Reference yield:

: 6530-09-2,119904-90-4,120538-52-5,123536-14-1,124577-62-4,126358-22-3,137661-30-4,137661-31-5
(3R)-quinuclidin-3-amine dihydrochloride

: 1404054-16-5
(R)-bis(3-fluorophenyl)methyl quinuclidin-3-ylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydrogencarbonate / water; methanol / 1 h / 20 °C

1.2: 7 h / 20 °C

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 0 - 20 °C

2.2: 48 h / 20 °C

With sodium hydride; sodium hydrogencarbonate; In methanol; water; N,N-dimethyl-formamide; mineral oil;