D,L-(1r,2c,3c,4t,6t)-4-O-benzoyl-3,6-bis(benzyloxycarbonylamino)-1,2,4-cyclohexanetriol

Base Information

Chemical Name:D,L-(1r,2c,3c,4t,6t)-4-O-benzoyl-3,6-bis(benzyloxycarbonylamino)-1,2,4-cyclohexanetriol
CAS No.:95058-21-2
Molecular Formula:C₂₉H₃₀N₂O₈
Molecular Weight:534.566
Hs Code.:

Synonyms:D,L-(1r,2c,3c,4t,6t)-4-O-benzoyl-3,6-bis(benzyloxycarbonylamino)-1,2,4-cyclohexanetriol

Suppliers and Price of D,L-(1r,2c,3c,4t,6t)-4-O-benzoyl-3,6-bis(benzyloxycarbonylamino)-1,2,4-cyclohexanetriol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of D,L-(1r,2c,3c,4t,6t)-4-O-benzoyl-3,6-bis(benzyloxycarbonylamino)-1,2,4-cyclohexanetriol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of D,L-(1r,2c,3c,4t,6t)-4-O-benzoyl-3,6-bis(benzyloxycarbonylamino)-1,2,4-cyclohexanetriol

There total 5 articles about D,L-(1r,2c,3c,4t,6t)-4-O-benzoyl-3,6-bis(benzyloxycarbonylamino)-1,2,4-cyclohexanetriol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 95058-20-1,99295-64-4,102735-34-2
Benzoic acid (1S,2R,3S,4R,5R)-2,5-bis-benzyloxycarbonylamino-3,4-dihydroxy-6-iodo-cyclohexyl ester

: 95058-21-2
D,L-(1r,2c,3c,4t,6t)-4-O-benzoyl-3,6-bis(benzyloxycarbonylamino)-1,2,4-cyclohexanetriol

Guidance literature:: With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In tetrahydrofuran; Heating;
DOI:10.1246/cl.1984.1665

Reference yield:

: 98-88-4
benzoyl chloride

: 95058-21-2
D,L-(1r,2c,3c,4t,6t)-4-O-benzoyl-3,6-bis(benzyloxycarbonylamino)-1,2,4-cyclohexanetriol

Guidance literature:: Multi-step reaction with 5 steps

1: 84 percent / pyridine / 21 h / Ambient temperature

2: 70 percent / pyridine

3: 93 percent / AcOH, H₂O / 2 h / 80 °C

4: 98 percent / NaI / dimethylformamide / 8 h / 100 °C

5: 96 percent / tri-n-butyl tin hydride, AIBN / tetrahydrofuran / Heating

With pyridine; 2,2'-azobis(isobutyronitrile); water; tri-n-butyl-tin hydride; acetic acid; sodium iodide; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1246/cl.1984.1665

Reference yield:

: 95058-17-6
Benzoic acid (3aR,4S,5R,6S,7R,7aS)-4,7-bis-benzyloxycarbonylamino-6-hydroxy-2,2-dimethyl-hexahydro-benzo[1,3]dioxol-5-yl ester

: 95058-21-2
D,L-(1r,2c,3c,4t,6t)-4-O-benzoyl-3,6-bis(benzyloxycarbonylamino)-1,2,4-cyclohexanetriol

Guidance literature:: Multi-step reaction with 4 steps

1: 70 percent / pyridine

2: 93 percent / AcOH, H₂O / 2 h / 80 °C

3: 98 percent / NaI / dimethylformamide / 8 h / 100 °C

4: 96 percent / tri-n-butyl tin hydride, AIBN / tetrahydrofuran / Heating

With pyridine; 2,2'-azobis(isobutyronitrile); water; tri-n-butyl-tin hydride; acetic acid; sodium iodide; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1246/cl.1984.1665