2-(4-Chlorophenyl)-4-quinazolinamine

Base Information

Chemical Name:2-(4-Chlorophenyl)-4-quinazolinamine
CAS No.:83702-21-0
Molecular Formula:C₁₄H₁₀ClN₃
Molecular Weight:255.707
Hs Code.:
DSSTox Substance ID:DTXSID701289725
Nikkaji Number:J2.827.808J

Synonyms:83702-21-0;DTXSID701289725;2-(4-Chlorophenyl)-4-quinazolinamine;AKOS010208108

Suppliers and Price of 2-(4-Chlorophenyl)-4-quinazolinamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-(4-Chlorophenyl)-4-quinazolinamine

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:255.0563250
Heavy Atom Count:18
Complexity:278

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=NC(=N2)C3=CC=C(C=C3)Cl)N

Technology Process of 2-(4-Chlorophenyl)-4-quinazolinamine

There total 7 articles about 2-(4-Chlorophenyl)-4-quinazolinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 122-01-0
4-chloro-benzoyl chloride

: 1885-29-6
anthranilic acid nitrile

: 83702-21-0
4-Amino-2-(4-chlorophenyl)quinazoline

Guidance literature:: With ammonium acetate; In acetonitrile; for 1h; Reflux;
DOI:10.1080/00397910903019967

Reference yield: 81.0%

: 885953-16-2
2-iodobenzimidamide

: 104-88-1
4-chlorobenzaldehyde

: 83702-21-0
4-Amino-2-(4-chlorophenyl)quinazoline

Guidance literature:: With sodium azide; L-proline; copper(I) bromide; In N,N-dimethyl-formamide; at 70 ℃;
DOI:10.1055/s-0036-1588727

Reference yield: 71.0%

: 2042-37-7
o-cyanobromobenzene

: 104-88-1
4-chlorobenzaldehyde

: 83702-21-0
4-Amino-2-(4-chlorophenyl)quinazoline

Guidance literature:: With iron(III) chloride; copper(l) iodide; sodium azide; L-proline; In N,N-dimethyl-formamide; at 110 ℃; for 12h; Sealed tube;
DOI:10.1021/acs.orglett.5b02020