pivaloyl chloride-2,4-dichloro-5-isopropoxy-N-phenylhydrazone

Base Information

• Chemical Name: pivaloyl chloride-2,4-dichloro-5-isopropoxy-N-phenylhydrazone
• CAS No.: 51166-88-2
• Molecular Formula: C₁₄H₁₉Cl₃N₂O
• Molecular Weight: 337.677
• Mol file: 51166-88-2.mol

Synonyms:pivaloyl chloride-2,4-dichloro-5-isopropoxy-N-phenylhydrazone

Chemical Property of pivaloyl chloride-2,4-dichloro-5-isopropoxy-N-phenylhydrazone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of pivaloyl chloride-2,4-dichloro-5-isopropoxy-N-phenylhydrazone

There total 2 articles about pivaloyl chloride-2,4-dichloro-5-isopropoxy-N-phenylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-trimethylacetyl-2-(2,4-dichloro-5-isopropoxyphenyl) hydrazine (51167-18-1) → pivaloyl chloride-2,4-dichloro-5-isopropoxy-N-phenylhydrazone (51166-88-2)

Guidance literature:

With tetrachloromethane; triphenylphosphine; In acetonitrile; at 20 ℃; for 12h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.joc.7b00963

Reference yield:

→ pivaloyl chloride-2,4-dichloro-5-isopropoxy-N-phenylhydrazone (51166-88-2)

Guidance literature:

entspr. Hydrazin, PCl5;

Reference yield: 88.0%

carbon dioxide (124-38-9,18923-20-1) + pivaloyl chloride-2,4-dichloro-5-isopropoxy-N-phenylhydrazone (51166-88-2) → 3-[2,4-dichloro-5-(1-methylethoxy)phenyl]-5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2(3H)-one (19666-30-9)

Guidance literature:

With 18-crown-6 ether; cesium fluoride; In toluene; at 25 ℃; for 12h; under 15001.5 Torr; Schlenk technique; Autoclave;

DOI:10.1021/acs.joc.7b00963

upstream raw materials:

1-trimethylacetyl-2-(2,4-dichloro-5-isopropoxyphenyl) hydrazine

Downstream raw materials:

3-[2,4-dichloro-5-(1-methylethoxy)phenyl]-5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2(3H)-one

Refernces