51167-18-1

Basic information

• Product Name: 2'-[2,4-dichloro-5-(1-methylethoxy)phenyl]-2,2-dimethylpropionohydrazide
• Synonyms: 2'-[2,4-dichloro-5-(1-methylethoxy)phenyl]-2,2-dimethylpropionohydrazide;N'-(2,4-dichloro-5-propan-2-yloxyphenyl)-2,2-dimethylpropanehydrazide
• CAS NO: 51167-18-1
• Molecular Formula: C₁₄H₂₀Cl₂N₂O₂
• Molecular Weight: 319.2268
• EINECS: 257-027-8
• Mol File: 51167-18-1.mol

Chemical Properties

• Boiling Point: 369.3°Cat760mmHg
• Flash Point: 177.2°C
• Appearance: /
• Density: 1.217g/cm³
• CAS DataBase Reference: 2'-[2,4-dichloro-5-(1-methylethoxy)phenyl]-2,2-dimethylpropionohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-[2,4-dichloro-5-(1-methylethoxy)phenyl]-2,2-dimethylpropionohydrazide(51167-18-1)
• EPA Substance Registry System: 2'-[2,4-dichloro-5-(1-methylethoxy)phenyl]-2,2-dimethylpropionohydrazide(51167-18-1)

Safety Data

• Hazardous Substances Data: 51167-18-1(Hazardous Substances Data)

Usage

Uses

Used in Pesticide Industry:
2'-[2,4-dichloro-5-(1-methylethoxy)phenyl]-2,2-dimethylpropionohydrazide is used as an impurity in the production of Indoxacarb-based insecticides for controlling lepidopteran larvae in household settings. Its presence is a result of the degradation process of the active ingredient, Indoxacarb, which is effective in combating pests such as cockroaches.

Upstream product

• 19666-30-9 3-[2,4-dichloro-5-(1-methylethoxy)phenyl]-5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2(3H)-one 
• 106969-07-7 2,4-dichloro-5-isopropoxyphenylhydrazine hydrochloride 
• 3282-30-2 pivaloyl chloride 

Downstream Products

• 51166-88-2 pivaloyl chloride-2,4-dichloro-5-isopropoxy-N-phenylhydrazone 

Relevant articles and documents

Synthetic method of oxadiazon intermediate

The invention discloses a synthetic method of an oxadiazon intermediate. The method comprises the steps: dissolving 2,4-dichloro-5-isopropoxyphenylhydrazine hydrochloride into a chloroform solvent; adding an alkali to complete neutralization at a certain temperature, then standing and separating water; and taking an organic phase, adding an inorganic alkali as an acid-binding agent, stirring and cooling, dropwise adding metered pivaloyl chloride when the temperature reaches a proper temperature, directly separating water after the acylation reaction is qualified through central control analysis to obtain an oxadiazon intermediate 2,4-dichloro-5-isopropoxyphenylhydrazine chloroform solution, and entering the next process. The method is simple to operate and simplified in process, a neutralizing and filtering process is omitted, and the production of alkalized wastewater is greatly reduced; in the acylation step, the inorganic alkali is used as the acid-binding agent, so that a large amount of high-COD and high-ammonia-nitrogen-value wastewater which is difficult to treat is effectively prevented from being generated by adding an organic alkali, the acid-binding agent recovery process is reduced, the labor intensity is greatly reduced, energy is saved, and the economic benefit and the environmental benefit are remarkable.

Microbial Degradation of Oxadiazon by Soil Fungus Fusarium solani

Degradation of oxadiazon 2-1,3,4-oxadiazolin-5-one (1)>, a preemergent soil-applied herbicide, by a soil fungus, Fusarium solani (Mortius) Sacc., has been investigated.F. solani, isolated from soil by enrichment culture technique, degraded the herbicide 1 by cometabolic process.Eleven metabolites have been isolated, out of which three metabolites (M1, M2, and M3) were characterized by spectroscopic evidence.Metabolites M1 and M3 are reported for the first time as metabolites of oxadiazon.The main metabolic pathways involve oxadiazoline ring cleavage without dechlorination reaction. - Keywords: degradation; cometabolism; metabolic pathway; oxadiazon; Fusarium solani.