2'-(2,4-Dichloro-5-(1-methylethoxy)phenyl)-2,2-dimethylpropionohydrazide

Base Information

• Chemical Name: 2'-(2,4-Dichloro-5-(1-methylethoxy)phenyl)-2,2-dimethylpropionohydrazide
• CAS No.: 51167-18-1
• Molecular Formula: C14H20Cl2N2O2
• Molecular Weight: 319.231
• Hs Code.: 2928000090
• European Community (EC) Number: 257-027-8
• DSSTox Substance ID: DTXSID10199191
• Nikkaji Number: J30.870F
• Wikidata: Q83072099
• Mol file: 51167-18-1.mol

Synonyms:51167-18-1;EINECS 257-027-8;2'-(2,4-Dichloro-5-(1-methylethoxy)phenyl)-2,2-dimethylpropionohydrazide;2'-[2,4-DICHLORO-5-(1-METHYLETHOXY)PHENYL]-2,2-DIMETHYLPROPIONOHYDRAZIDE;N'-(2,4-dichloro-5-propan-2-yloxyphenyl)-2,2-dimethylpropanehydrazide;EC 257-027-8;N'-(2,4-Dichloro-5-isopropoxyphenyl)pivalohydrazide;starbld0005621;DTXSID10199191;IRVAUMHWBDVRPH-UHFFFAOYSA-N;N'-(2,4-Dichloro-5-isopropoxyphenyl)pivalic acid hydrazide;Propanoic acid, 2,2-dimethyl-, 2-(2,4-dichloro-5-(1-methylethoxy)phenyl)hydrazide

Chemical Property of 2'-(2,4-Dichloro-5-(1-methylethoxy)phenyl)-2,2-dimethylpropionohydrazide

Chemical Property:

• Boiling Point: 369.3°Cat760mmHg
• Flash Point: 177.2°C
• PSA: 53.85000
• Density: 1.217g/cm³
• LogP: 5.18310
• XLogP3: 4.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 318.0901833
• Heavy Atom Count: 20
• Complexity: 332

Purity/Quality:

99.9% ^*data from raw suppliers

1-Trimethylacetyl-2-(2,4-dichloro-5-isopropoxyphenyl)hydrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)OC1=C(C=C(C(=C1)NNC(=O)C(C)(C)C)Cl)Cl
• Uses: 1-Trimethylacetyl-2-(2,4-dichloro-5-isopropoxyphenyl)hydrazine is an impurity found from the degredation of Indoxacarb (I654000), an oxadiazine pesticide that acts against lepidopteran larvae and is the active ingredient in a number of household insecticides including cockroach baits.

Technology Process of 2'-(2,4-Dichloro-5-(1-methylethoxy)phenyl)-2,2-dimethylpropionohydrazide

There total 3 articles about 2'-(2,4-Dichloro-5-(1-methylethoxy)phenyl)-2,2-dimethylpropionohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2,4-dichloro-5-isopropoxyphenylhydrazine hydrochloride (106969-07-7) + pivaloyl chloride (3282-30-2) → 1-trimethylacetyl-2-(2,4-dichloro-5-isopropoxyphenyl) hydrazine (51167-18-1)

Guidance literature:

2,4-dichloro-5-isopropoxyphenylhydrazine hydrochloride; In chloroform; at 20 ℃; pH=10; Alkaline conditions;

pivaloyl chloride; In chloroform; at 10 - 15 ℃; Temperature;

Reference yield:

3-[2,4-dichloro-5-(1-methylethoxy)phenyl]-5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2(3H)-one (19666-30-9) → 2,4-dichloro-1-isopropoxybenzene (6851-40-7) + 1-trimethylacetyl-2-(2,4-dichloro-5-isopropoxyphenyl) hydrazine (51167-18-1) + 1-(2,4-dichloro-5-isopropoxyphenyl)-1-(methoxycarbonyl)-1,2-trimethylacetyl hydrazine (56578-26-8)

Guidance literature:

In methanol; water; at 28 ℃; Fusarium solani (Mortius) Sacc_.; also in the presence of dextrose; rate of degradation;

DOI:10.1021/jf00059a035

Reference yield:

→ 1-trimethylacetyl-2-(2,4-dichloro-5-isopropoxyphenyl) hydrazine (51167-18-1)

Guidance literature:

Entspr. Hydrazin, Trimethylacetylchlorid;

upstream raw materials:

3-[2,4-dichloro-5-(1-methylethoxy)phenyl]-5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2(3H)-one

2,4-dichloro-5-isopropoxyphenylhydrazine hydrochloride

pivaloyl chloride

Downstream raw materials:

pivaloyl chloride-2,4-dichloro-5-isopropoxy-N-phenylhydrazone

Refernces

• 1、 Chakraborty, Subhasish K.,Chowdhury, Ashim,Bhattacharyya, Anjan,Ghosh, Swapan,Pan, Sitangsu,et al.. "Microbial Degradation of Oxadiazon by Soil Fungus Fusarium solani". . p. 2964 - 2969. Retrieved 2007/10/03.