Ethanone, 1-bicyclo[2.2.2]oct-5-en-2-yl-, [1R-(1alpha,2beta,4alpha)]- (9CI)

Base Information

• Chemical Name: Ethanone, 1-bicyclo[2.2.2]oct-5-en-2-yl-, [1R-(1alpha,2beta,4alpha)]- (9CI)
• CAS No.: 155156-90-4
• Molecular Formula: C₁₀H₁₄O
• Molecular Weight: 150.221
• Mol file: 155156-90-4.mol

Synonyms:Ethanone,1-bicyclo[2.2.2]oct-5-en-2-yl-, [1R-(1a,2b,4a)]- (9CI)

Chemical Property of Ethanone, 1-bicyclo[2.2.2]oct-5-en-2-yl-, [1R-(1alpha,2beta,4alpha)]- (9CI)

Chemical Property:

• Boiling Point: 224.8±29.0 °C(Predicted)
• PSA: 17.07000
• Density: 1.018±0.06 g/cm3(Predicted)
• LogP: 2.17770

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ethanone, 1-bicyclo[2.2.2]oct-5-en-2-yl-, [1R-(1alpha,2beta,4alpha)]- (9CI)

There total 12 articles about Ethanone, 1-bicyclo[2.2.2]oct-5-en-2-yl-, [1R-(1alpha,2beta,4alpha)]- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

methyl vinyl ketone (78-94-4,25038-87-3) + cyclohexa-1,3-diene (1165952-91-9) → bicyclo(2.2.2)-5-octene-2-carboxaldehyde (40590-77-0,155156-91-5,155156-90-4,185303-22-4)

Guidance literature:

[Ru(N,N'-ethylenebis(salicylideneaminate)(NO)(H₂O)](SbF₆); In nitromethane-d3; at 25 ℃; for 22h;

DOI:10.1016/S0040-4020(01)87259-8

Reference yield: 75.0%

methyl vinyl ketone (78-94-4,25038-87-3) + cyclohexene (110-83-8) → bicyclo(2.2.2)-5-octene-2-carboxaldehyde (40590-77-0,155156-91-5,155156-90-4,185303-22-4)

Guidance literature:

With tin(IV) chloride; In dichloromethane; at 0 ℃; for 1.5h; Inert atmosphere;

Reference yield:

methyl vinyl ketone (78-94-4,25038-87-3) → bicyclo(2.2.2)-5-octene-2-carboxaldehyde (40590-77-0,155156-91-5,155156-90-4,185303-22-4)

Guidance literature:

methyl vinyl ketone; [hydridotris(pyrazolyl)borate]Mo(NO)(1-methylimidazole)(η²-1,3-cyclohexadiene); With methanol; In dichloromethane; at 25 ℃; for 96h;

In acetone; for 1h;

DOI:10.1021/ja0553654

upstream raw materials:

methyl vinyl ketone

cyclohexa-1,3-diene

acrolein

cyclohexene

Downstream raw materials:

Bicyclo<2.2.2>oct-2-ylmethylketon