3-phenylpropyl 2-(trimethylsilyl)ethyl sulfide

Base Information

• Chemical Name: 3-phenylpropyl 2-(trimethylsilyl)ethyl sulfide
• CAS No.: 114764-11-3
• Molecular Formula: C₁₄H₂₄SSi
• Molecular Weight: 252.496
• Mol file: 114764-11-3.mol

Synonyms:3-phenylpropyl 2-(trimethylsilyl)ethyl sulfide

Chemical Property of 3-phenylpropyl 2-(trimethylsilyl)ethyl sulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-phenylpropyl 2-(trimethylsilyl)ethyl sulfide

There total 2 articles about 3-phenylpropyl 2-(trimethylsilyl)ethyl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-trimethylsilylethanethiol (18143-30-1) + 1-Bromo-3-phenylpropane (637-59-2) → 3-phenylpropyl 2-(trimethylsilyl)ethyl sulfide (114764-11-3)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane;

DOI:10.1021/jo00248a045

Reference yield:

3-methylbutyl 3-phenylpropyl sulfide (410080-31-8) → 3-phenylpropyl 2-(trimethylsilyl)ethyl sulfide (114764-11-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: methanol / 20 °C

2.1: sodium hydride / tetrahydrofuran / 0.5 h / 20 °C

2.2: 68 percent / tetrahydrofuran / 15 h / 20 °C

With sodium hydride; In tetrahydrofuran; methanol; 1.1: von Braun reaction;

DOI:10.1021/jo016200q

Reference yield: 4.0%

dimethyl(methylthio)sulfonium tetrafluoroborate (5799-67-7) + 3-phenylpropyl 2-(trimethylsilyl)ethyl sulfide (114764-11-3) → 1,2-bis(3-phenylpropyl)disulfane (89987-96-2) + (3-Methyldisulfanyl-propyl)-benzene (114764-12-4)

Guidance literature:

With Dimethyldisulphide; In dichloromethane; at 0 ℃; for 4h; Title compound not separated from byproducts;

DOI:10.1021/jo00248a045

upstream raw materials:

2-trimethylsilylethanethiol

1-Bromo-3-phenylpropane

3-methylbutyl 3-phenylpropyl sulfide

Downstream raw materials:

1,2-bis(3-phenylpropyl)disulfane

(3-Methyldisulfanyl-propyl)-benzene

S-(3-phenylpropyl) ethanethioate

(3-thiocyanatopropyl)benzene