N-methyl-N'-{3-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]phenyl}acetohydrazide

Base Information

Chemical Name:N-methyl-N'-{3-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]phenyl}acetohydrazide
CAS No.:1237587-17-5
Molecular Formula:C₁₉H₁₆Cl₂F₃N₃O₂
Molecular Weight:446.256
Hs Code.:

Synonyms:N-methyl-N'-{3-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]phenyl}acetohydrazide

Suppliers and Price of N-methyl-N'-{3-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]phenyl}acetohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-methyl-N'-{3-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]phenyl}acetohydrazide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-methyl-N'-{3-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]phenyl}acetohydrazide

There total 12 articles about N-methyl-N'-{3-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]phenyl}acetohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1237587-16-4
tert-butyl N'-acetyl-N'-methyl-N-{3-[5-(3,5-dichlorophenyl)-5-trifluoro methyl-4,5-dihydroisoxazol-3-yl]phenyl}carbazate

: 1237587-17-5
N-methyl-N'-{3-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]phenyl}acetohydrazide

Guidance literature:: tert-butyl N'-acetyl-N'-methyl-N-{3-[5-(3,5-dichlorophenyl)-5-trifluoro methyl-4,5-dihydroisoxazol-3-yl]phenyl}carbazate; With trifluoroacetic acid; at 20 ℃; for 0.5h;

With sodium hydrogencarbonate; In water; ethyl acetate;

Reference yield:

: 3431-62-7,20747-39-1
3-nitrobenzaldoxime

: 1237587-17-5
N-methyl-N'-{3-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]phenyl}acetohydrazide

Guidance literature:: Multi-step reaction with 8 steps

1.1: N-chloro-succinimide / N,N-dimethyl-formamide / 1 h / 60 °C

1.2: 6 h / 20 °C

2.1: acetic acid; iron / ethanol; water / 1.25 h / 20 - 75 °C

3.1: triethylamine / tetrahydrofuran / 0.25 h / 0 °C

4.1: 4-dimethylpyridine / tetrahydrofuran / 1.5 h / 20 °C

5.1: sodium hydroxide; sodium hypochlorite; ammonia; ammonium chloride / Aliquat 336 / water; tert-butyl methyl ether / 12.33 h / 20 °C

6.1: triethylamine / tetrahydrofuran / 14 h / 0 - 20 °C

7.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 20 °C

7.2: 10 h / 20 °C

8.1: trifluoroacetic acid / tetrahydrofuran / 0.5 h / 20 °C

With sodium hypochlorite; N-chloro-succinimide; ammonia; iron; sodium hydride; ammonium chloride; acetic acid; triethylamine; trifluoroacetic acid; sodium hydroxide; Aliquat 336; In tetrahydrofuran; ethanol; tert-butyl methyl ether; water; N,N-dimethyl-formamide; mineral oil;

Reference yield:

: 1070396-59-6
3-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]aniline

: 1237587-17-5
N-methyl-N'-{3-[5-(3,5-dichlorophenyl)-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]phenyl}acetohydrazide

Guidance literature:: Multi-step reaction with 6 steps

1.1: triethylamine / tetrahydrofuran / 0.25 h / 0 °C

2.1: 4-dimethylpyridine / tetrahydrofuran / 1.5 h / 20 °C

3.1: sodium hydroxide; sodium hypochlorite; ammonia; ammonium chloride / Aliquat 336 / water; tert-butyl methyl ether / 12.33 h / 20 °C

4.1: triethylamine / tetrahydrofuran / 14 h / 0 - 20 °C

5.1: sodium hydride / tetrahydrofuran; mineral oil / 0.5 h / 20 °C

5.2: 10 h / 20 °C

6.1: trifluoroacetic acid / tetrahydrofuran / 0.5 h / 20 °C

With sodium hypochlorite; ammonia; sodium hydride; ammonium chloride; triethylamine; trifluoroacetic acid; sodium hydroxide; Aliquat 336; In tetrahydrofuran; tert-butyl methyl ether; water; mineral oil;