dimethyl 5-(aminomethyl)benzene-1,3-dioate

Base Information

Chemical Name:dimethyl 5-(aminomethyl)benzene-1,3-dioate
CAS No.:1220529-82-7
Molecular Formula:C₁₁H₁₃NO₄
Molecular Weight:223.229
Hs Code.:
Mol file:1220529-82-7.mol

Synonyms:dimethyl 5-(azidomethyl)isophthalate

Suppliers and Price of dimethyl 5-(aminomethyl)benzene-1,3-dioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

American Custom Chemicals Corporation
DIMETHYL 5-(AMINOMETHYL)BENZENE-1,3-DIOATE 95.00%
5MG
$ 497.67

Total 1 raw suppliers

Chemical Property of dimethyl 5-(aminomethyl)benzene-1,3-dioate

Chemical Property:

Purity/Quality:: DIMETHYL 5-(AMINOMETHYL)BENZENE-1,3-DIOATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of dimethyl 5-(aminomethyl)benzene-1,3-dioate

There total 5 articles about dimethyl 5-(aminomethyl)benzene-1,3-dioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 178056-30-9
dimethyl 5-azidomethylbenzene-1,3-dicarboxylate

: 1220529-82-7
dimethyl 5-(azidomethyl)isophthalate

Guidance literature:: With triphenylphosphine; In tetrahydrofuran; water; at 20 ℃; for 12h;
DOI:10.1021/ja3085884

Reference yield:

: 252210-01-8
dimethyl 5-chloromethyl-1,3-benzenedicarboxylate

: 1220529-82-7
dimethyl 5-(azidomethyl)isophthalate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium azide / acetone; water / 14 h / Reflux

2: tributylphosphine / diethyl ether / 0.75 h / 20 °C

With sodium azide; tributylphosphine; In diethyl ether; water; acetone;

Reference yield:

: 38588-64-6
3,5-bis(methoxycarbonyl)benzoic acid

: 1220529-82-7
dimethyl 5-(azidomethyl)isophthalate

Guidance literature:: Multi-step reaction with 4 steps

1: dimethylsulfide borane complex / tetrahydrofuran / 24 h / 20 °C

2: thionyl chloride / 1.5 h / Inert atmosphere; Reflux

3: sodium azide / water; acetone / Reflux

4: triphenylphosphine; water / tetrahydrofuran / 10 h / 20 °C

With thionyl chloride; sodium azide; dimethylsulfide borane complex; water; triphenylphosphine; In tetrahydrofuran; water; acetone;
DOI:10.1021/acs.jmedchem.6b01892