5-(Methoxycarbonyl)-2-nitrophenylacetic acid methyl ester

Base Information

Chemical Name:5-(Methoxycarbonyl)-2-nitrophenylacetic acid methyl ester
CAS No.:154078-86-1
Molecular Formula:C11H11 N O6
Molecular Weight:253.21
Hs Code.:
DSSTox Substance ID:DTXSID60439312
Wikidata:Q82255231
Mol file:154078-86-1.mol

Synonyms:154078-86-1;5-(METHOXYCARBONYL)-2-NITROPHENYLACETIC ACID METHYL ESTER;methyl 3-(2-methoxy-2-oxoethyl)-4-nitrobenzoate;DTXSID60439312;AKOS027383600

Suppliers and Price of 5-(Methoxycarbonyl)-2-nitrophenylacetic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5-(METHOXYCARBONYL)-2-NITROPHENYLACETIC ACID METHYL ESTER 98.00%
5MG
$ 498.12

Total 9 raw suppliers

Chemical Property of 5-(Methoxycarbonyl)-2-nitrophenylacetic acid methyl ester

Chemical Property:

Boiling Point:385.2±37.0 °C(Predicted)
PSA：98.42000
Density:1.318±0.06 g/cm3(Predicted)
LogP:1.62010
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:253.05863707
Heavy Atom Count:18
Complexity:337

Purity/Quality:

98%Min ^*data from raw suppliers

5-(METHOXYCARBONYL)-2-NITROPHENYLACETIC ACID METHYL ESTER 98.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CC1=C(C=CC(=C1)C(=O)OC)[N+](=O)[O-]

Technology Process of 5-(Methoxycarbonyl)-2-nitrophenylacetic acid methyl ester

There total 3 articles about 5-(Methoxycarbonyl)-2-nitrophenylacetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 76143-33-4
5-(methoxycarbonyl)-2-nitrobenzoic acid

: 154078-86-1
methyl 5-(methoxycarbonyl)-2-nitrophenylacetate

Guidance literature:: Multi-step reaction with 3 steps

1: SOCl₂ / dimethylformamide / 0.75 h / Heating

2: benzene; diethyl ether / 2 h / 20 °C

3: Ag₂O / 0.5 h / Heating

With thionyl chloride; silver(l) oxide; In diethyl ether; N,N-dimethyl-formamide; benzene;
DOI:10.1021/jm00029a009

Reference yield:

: 3-Chlorocarbonyl-4-nitro-benzoic acid methyl ester

: 154078-86-1
methyl 5-(methoxycarbonyl)-2-nitrophenylacetate

Guidance literature:: Multi-step reaction with 2 steps

1: benzene; diethyl ether / 2 h / 20 °C

2: Ag₂O / 0.5 h / Heating

With silver(l) oxide; In diethyl ether; benzene;
DOI:10.1021/jm00029a009