methyl 4,6-O-benzylidene-3-deoxy-3-C-ethyl-α-D-altropyranoside

Base Information

• Chemical Name: methyl 4,6-O-benzylidene-3-deoxy-3-C-ethyl-α-D-altropyranoside
• CAS No.: 626200-80-4
• Molecular Formula: C₁₆H₂₂O₅
• Molecular Weight: 294.348
• Mol file: 626200-80-4.mol

Synonyms:methyl 4,6-O-benzylidene-3-deoxy-3-C-ethyl-α-D-altropyranoside

Chemical Property of methyl 4,6-O-benzylidene-3-deoxy-3-C-ethyl-α-D-altropyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 4,6-O-benzylidene-3-deoxy-3-C-ethyl-α-D-altropyranoside

There total 3 articles about methyl 4,6-O-benzylidene-3-deoxy-3-C-ethyl-α-D-altropyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

chloroethane (75-00-3) + methyl 2,3-anhydro-4,6-O-benzilidene-α-D-mannopyranoside (3150-15-0,3150-16-1,3257-59-8,14187-71-4,15384-57-3,19465-13-5,32976-15-1,52885-37-7,53270-02-3,53270-03-4,65391-11-9,65391-12-0,66537-92-6,67226-04-4,71184-14-0,86420-78-2,86420-79-3,91177-51-4,91177-52-5,117708-93-7,120408-72-2,2880-96-8) → methyl 4,6-O-benzylidene-3-deoxy-3-C-ethyl-α-D-altropyranoside (626200-80-4)

Guidance literature:

chloroethane; With iodine; magnesium; In tetrahydrofuran; toluene; at 70 ℃;

methyl 2,3-anhydro-4,6-O-benzilidene-α-D-mannopyranoside; In tetrahydrofuran; toluene; at 110 ℃; for 1h;

Reference yield: 74.0%

ethylmagnesium chloride (2386-64-3) + methyl 2,3-anhydro-4,6-O-benzilidene-α-D-mannopyranoside (3150-15-0,3150-16-1,3257-59-8,14187-71-4,15384-57-3,19465-13-5,32976-15-1,52885-37-7,53270-02-3,53270-03-4,65391-11-9,65391-12-0,66537-92-6,67226-04-4,71184-14-0,86420-78-2,86420-79-3,91177-51-4,91177-52-5,117708-93-7,120408-72-2,2880-96-8) → methyl 4,6-O-benzylidene-3-deoxy-3-C-ethyl-α-D-altropyranoside (626200-80-4)

Guidance literature:

In toluene;

DOI:10.1016/S0960-894X(03)00739-X

Reference yield:

diethylmagnesium (557-18-6) + methyl 2,3-anhydro-4,6-O-benzilidene-α-D-mannopyranoside (3150-15-0,3150-16-1,3257-59-8,14187-71-4,15384-57-3,19465-13-5,32976-15-1,52885-37-7,53270-02-3,53270-03-4,65391-11-9,65391-12-0,66537-92-6,67226-04-4,71184-14-0,86420-78-2,86420-79-3,91177-51-4,91177-52-5,117708-93-7,120408-72-2,2880-96-8) → methyl 4,6-O-benzylidene-3-deoxy-3-C-ethyl-α-D-altropyranoside (626200-80-4)

Guidance literature:

With diethyl ether; magnesium iodide;

upstream raw materials:

diethylmagnesium

methyl 2,3-anhydro-4,6-O-benzilidene-α-D-mannopyranoside

ethylmagnesium chloride

chloroethane

Downstream raw materials:

Benzoic acid (1R,2S,3S)-2-ethyl-3,4-dihydroxy-1-vinyl-butyl ester

Benzoic acid (1R,2R)-2-(S)-oxiranyl-1-vinyl-butyl ester

Benzoic acid (2S,3S,4S,5S,6S)-2-bromomethyl-4-ethyl-5-hydroxy-6-methoxy-tetrahydro-pyran-3-yl ester