methyl N-((2S)-2-{(7S)-7-[(1S)-1-azido-2-(4-hydroxyphenyl)-ethyl]-3-oxo-1,4-oxazepan-4-yl}-3-phenylpropanoyl)-L-leucinate

Base Information

Chemical Name:methyl N-((2S)-2-{(7S)-7-[(1S)-1-azido-2-(4-hydroxyphenyl)-ethyl]-3-oxo-1,4-oxazepan-4-yl}-3-phenylpropanoyl)-L-leucinate
CAS No.:880489-95-2
Molecular Formula:C₂₉H₃₇N₅O₆
Molecular Weight:551.643
Hs Code.:

Synonyms:methyl N-((2S)-2-{(7S)-7-[(1S)-1-azido-2-(4-hydroxyphenyl)-ethyl]-3-oxo-1,4-oxazepan-4-yl}-3-phenylpropanoyl)-L-leucinate

Suppliers and Price of methyl N-((2S)-2-{(7S)-7-[(1S)-1-azido-2-(4-hydroxyphenyl)-ethyl]-3-oxo-1,4-oxazepan-4-yl}-3-phenylpropanoyl)-L-leucinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl N-((2S)-2-{(7S)-7-[(1S)-1-azido-2-(4-hydroxyphenyl)-ethyl]-3-oxo-1,4-oxazepan-4-yl}-3-phenylpropanoyl)-L-leucinate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl N-((2S)-2-{(7S)-7-[(1S)-1-azido-2-(4-hydroxyphenyl)-ethyl]-3-oxo-1,4-oxazepan-4-yl}-3-phenylpropanoyl)-L-leucinate

There total 1 articles about methyl N-((2S)-2-{(7S)-7-[(1S)-1-azido-2-(4-hydroxyphenyl)-ethyl]-3-oxo-1,4-oxazepan-4-yl}-3-phenylpropanoyl)-L-leucinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 246158-11-2
tert-butyl [(1S,2S)-2-azido-3-(4-tert-butoxyphenyl)-1-(2-oxoethyl)propoxy]acetate

: 880489-95-2
methyl N-((2S)-2-{(7S)-7-[(1S)-1-azido-2-(4-hydroxyphenyl)-ethyl]-3-oxo-1,4-oxazepan-4-yl}-3-phenylpropanoyl)-L-leucinate

: 35661-40-6
N-Fmoc L-Phe

Guidance literature:: Multistep reaction;
DOI:10.1039/b515618a

Reference yield:

: 880489-95-2
methyl N-((2S)-2-{(7S)-7-[(1S)-1-azido-2-(4-hydroxyphenyl)-ethyl]-3-oxo-1,4-oxazepan-4-yl}-3-phenylpropanoyl)-L-leucinate

: 880489-96-3
2-(2-{7-[1-amino-2-(4-hydroxy-phenyl)-ethyl]-3-oxo-[1,4]oxazepan-4-yl}-3-phenyl-propionylamino)-4-methyl-pentanoic acid methyl ester

Guidance literature:: With TEA; thiophenol; tin(ll) chloride; In tetrahydrofuran;
DOI:10.1039/b515618a

Reference yield:

: 880489-95-2
methyl N-((2S)-2-{(7S)-7-[(1S)-1-azido-2-(4-hydroxyphenyl)-ethyl]-3-oxo-1,4-oxazepan-4-yl}-3-phenylpropanoyl)-L-leucinate

: N-((2S)-2-{(7S)-7-[(1S)-1-amino-2-(4-hydroxyphenyl)ethyl]-3-oxo-1,4-oxazepan-4-yl}-3-phenylpropanoyl)-L-leucine

Guidance literature:: Multi-step reaction with 2 steps

1: SnCl₂; PhSH; TEA / tetrahydrofuran

2: aq. LiOH / tetrahydrofuran / 5 h

With lithium hydroxide; TEA; thiophenol; tin(ll) chloride; In tetrahydrofuran;
DOI:10.1039/b515618a