N-(4-chlorobenzenesulfonyl)imidoylacetic acid (acetylethoxycarbonyl)methyl ester

Base Information

• Chemical Name: N-(4-chlorobenzenesulfonyl)imidoylacetic acid (acetylethoxycarbonyl)methyl ester
• CAS No.: 960161-58-4
• Molecular Formula: C₁₄H₁₆ClNO₆S
• Molecular Weight: 361.803
• Mol file: 960161-58-4.mol

Synonyms:N-(4-chlorobenzenesulfonyl)imidoylacetic acid (acetylethoxycarbonyl)methyl ester

Chemical Property of N-(4-chlorobenzenesulfonyl)imidoylacetic acid (acetylethoxycarbonyl)methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-chlorobenzenesulfonyl)imidoylacetic acid (acetylethoxycarbonyl)methyl ester

There total 1 articles about N-(4-chlorobenzenesulfonyl)imidoylacetic acid (acetylethoxycarbonyl)methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

ethyl 2-diazo-3-oxobutanoate (2009-97-4) + N-((4-chlorophenyl)sulfonyl)acetamide (55379-05-0) → N-(4-chlorobenzenesulfonyl)imidoylacetic acid (acetylethoxycarbonyl)methyl ester (960161-58-4)

Guidance literature:

dirhodium tetraacetate; In dichloromethane; at 20 ℃;

DOI:10.1039/b508317f

Reference yield: 58.0%

N-(4-chlorobenzenesulfonyl)imidoylacetic acid (acetylethoxycarbonyl)methyl ester (960161-58-4) → 4-Chlorobenzenesulfonamide (98-64-6)

Guidance literature:

In methanol; for 5h; Heating;

DOI:10.1134/S1070428006120074

Reference yield: 58.0%

N-(4-chlorobenzenesulfonyl)imidoylacetic acid (acetylethoxycarbonyl)methyl ester (960161-58-4) + phenylhydrazine (100-63-0) → 5-methyl-2-phenyl-4-(2-phenylhydrazono)-2,4-dihydro-3H-pyrazol-3-one (7625-02-7)

Guidance literature:

N-(4-chlorobenzenesulfonyl)imidoylacetic acid (acetylethoxycarbonyl)methyl ester; In methanol; for 5h; Heating;

With selenium(IV) oxide; In methanol; at 20 ℃; for 10h;

phenylhydrazine; In methanol; at 18 - 20 ℃; for 3h;

DOI:10.1134/S1070428006120074

upstream raw materials:

ethyl 2-diazo-3-oxobutanoate

N-((4-chlorophenyl)sulfonyl)acetamide

Downstream raw materials:

4-Chlorobenzenesulfonamide

5-methyl-2-phenyl-4-(2-phenylhydrazono)-2,4-dihydro-3H-pyrazol-3-one

Refernces

• 1、 Selivanova,Nikolaev,Kostikov,Nikolaev,Siler,Schulze. "Chemistry of diazocarbonyl compounds: XXVIII. Reaction of acyclic N-arylsulfonylacetamides with Rh(II)-carbenoids as a new synthetic route to alkyl acetimidoates". . p. 1792 - 1799. Retrieved 2007/10/03.